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Lutonarin attenuates LPS-induced intestinal epithelial barrier dysfunction:a functional and transcriptomic analysis

Qian Du Jing Li Guyanan Li Zihan Wang Siran Yu Lihua Wang Xiangyu Guo Dali Wang Bin Hui Yuehua Tu Wenguang Sun Xuan Zhang Wei Chen

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1548-1551,4.

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1548-1551,4.DOI:10.3724/abbs.2025069

Lutonarin attenuates LPS-induced intestinal epithelial barrier dysfunction:a functional and transcriptomic analysis

Qian Du ¹Jing Li ¹Guyanan Li ¹Zihan Wang ¹Siran Yu ¹Lihua Wang ¹Xiangyu Guo ²Dali Wang ³Bin Hui ⁴Yuehua Tu ⁵Wenguang Sun ⁶Xuan Zhang ⁷Wei Chen⁸

作者信息

1. College of Public Health,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China
2. College of Public Health,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China Key Laboratory of Cellular Function and Pharmacology of Jilin Province,Yanbian University,Yanji 133002,China
3. Center for Clinical and Translational Medicine,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China
4. Joint Innovation Laboratory for Cell Therapy Technology,Shanghai University of Medicine&Health Sciences,Shanghai 201318,China
5. Department of Nutrition,Shanghai Sixth People''s Hospital,Shanghai 200233,China
6. International Peace Maternity and Child Health Hospital,Shanghai Jiao Tong University,School of Medicine,Shanghai 200030,China
7. Shanghai-MOST Key Laboratory of Health and Disease Genomics,NHC Key Lab of Reproduction Regulation,Shanghai Institute for Biomedical and Pharmaceutical Technologies,Medical School,Fudan University,Shanghai 200237,China
8. College of Public Health,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China Key Laboratory of Cellular Function and Pharmacology of Jilin Province,Yanbian University,Yanji 133002,China Joint Innovation Laboratory for Cell Therapy Technology,Shanghai University of Medicine&Health Sciences,Shanghai 201318,China Institute of Wound Prevention and Treatment,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China
折叠

摘要

关键词

inflammatory bowel disease ibd/chronic intestinal inflammation/Lutonarin/LPS induced/Intestinal epithelial barrier/Inflammation/disruption intestinal epithelial barrier ieb/intestinal homeostasispreventing

分类

医药卫生

引用本文复制引用

Qian Du,Jing Li,Guyanan Li,Zihan Wang,Siran Yu,Lihua Wang,Xiangyu Guo,Dali Wang,Bin Hui,Yuehua Tu,Wenguang Sun,Xuan Zhang,Wei Chen..Lutonarin attenuates LPS-induced intestinal epithelial barrier dysfunction:a functional and transcriptomic analysis[J].Acta Biochimica et Biophysica Sinica,2025,57(9):P.1548-1551,4.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.32170805) （No.32170805）

the Natural Science Foundation of Shanghai Municipality(No.23ZR1427300) （No.23ZR1427300）

Shanghai University of Medicine&Health Sciences School-Level Research Projects(No.SSF-24-22-02) （No.SSF-24-22-02）

the Shanghai University of Medicine&Health Sciences Faculty Talent Pool-Industry-Academia-Research Practice Program(No.202417). （No.202417）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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