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Integrated multi-omics and experimental approaches identify fascin actin-bundling protein 1 as an unfavorable prognostic biomarker in adrenocortical carcinoma

Pingkaiqi He Yihao Chen Ming Xi Shanshan Mo Jiahong Chen Chuanfan Zhong Fengping Liu Weide Zhong Le Zhang Junhong Deng Jianming Lu Chao Cai

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1406-1419,14.

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1406-1419,14.DOI:10.3724/abbs.2025067

Integrated multi-omics and experimental approaches identify fascin actin-bundling protein 1 as an unfavorable prognostic biomarker in adrenocortical carcinoma

Pingkaiqi He ¹Yihao Chen ²Ming Xi ³Shanshan Mo ⁴Jiahong Chen ²Chuanfan Zhong ⁵Fengping Liu ⁶Weide Zhong ⁷Le Zhang ⁸Junhong Deng ⁴Jianming Lu ⁹Chao Cai¹⁰

作者信息

1. Department of Urology,Minimally Invasive Surgery Center,The First Affiliated Hospital of Guangzhou Medical University,Guangdong Key Laboratory of Urology,Guangzhou Institute of Urology,Guangzhou 510120,China Department of Andrology,Guangzhou First People''s Hospital,Guangzhou Medical University,Guangzhou 510180,China
2. Department of Urology,Huizhou Municipal Central Hospital,Huizhou 516001,China
3. Department of Urology,Huadu District People''s Hospital,Southern Medical University,Guangzhou 510800,China
4. Department of Andrology,Guangzhou First People''s Hospital,Guangzhou Medical University,Guangzhou 510180,China
5. Department of Urology,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China
6. State Key Laboratory of Quality Research in Chinese Medicine,Macao University of Science and Technology,Macao 999078,China
7. State Key Laboratory of Quality Research in Chinese Medicine,Macao University of Science and Technology,Macao 999078,China Department of Urology,Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics,Guangzhou First People''s Hospital,Guangzhou Medical University,Guangzhou 510180,China
8. Institute for Integrative Genome Biology,University of California,Riverside 92507,USA
9. Department of Andrology,Guangzhou First People''s Hospital,Guangzhou Medical University,Guangzhou 510180,China Department of Urology,Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics,Guangzhou First People''s Hospital,Guangzhou Medical University,Guangzhou 510180,China
10. Department of Urology,Minimally Invasive Surgery Center,The First Affiliated Hospital of Guangzhou Medical University,Guangdong Key Laboratory of Urology,Guangzhou Institute of Urology,Guangzhou 510120,China
折叠

摘要

关键词

adrenocortical carcinoma/ATAC-seq/FSCN1/multi-omics/prognosis

分类

医药卫生

引用本文复制引用

Pingkaiqi He,Yihao Chen,Ming Xi,Shanshan Mo,Jiahong Chen,Chuanfan Zhong,Fengping Liu,Weide Zhong,Le Zhang,Junhong Deng,Jianming Lu,Chao Cai..Integrated multi-omics and experimental approaches identify fascin actin-bundling protein 1 as an unfavorable prognostic biomarker in adrenocortical carcinoma[J].Acta Biochimica et Biophysica Sinica,2025,57(9):P.1406-1419,14.

基金项目

supported by the grants from the National Natural Science Foundation of China(Nos.82073294 and 82003271) （Nos.82073294 and 82003271）

Youth Medical Innovation and Practice Research Program of Guangzhou(No.2023QNYXZD001) （No.2023QNYXZD001）

Guangzhou Planned Project of Science and Technology(Nos.2023A04J1269 and 202102010152) （Nos.2023A04J1269 and 202102010152）

Guangzhou Municipal Science and the Technology Key Project(No.202102080624) （No.202102080624）

Guangzhou Medical Key Subject Construction Project[20212023]. （）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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