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Modulation of ferroptosis via YY1-SLC7A11 axis in hepatic ischemia-reperfusion injury pathogenesis

Shaochuang Wang Baofei Jiang Jun Cao Ting Xu Chengming Zhou Xiangyou Yu Yi Wang Yu Xie Lindong Ji Guangrong Zhou Hao Wen Long Ma Kun Wu

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1391-1405,15.

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(9)：P.1391-1405,15.DOI:10.3724/abbs.2025093

Modulation of ferroptosis via YY1-SLC7A11 axis in hepatic ischemia-reperfusion injury pathogenesis

Shaochuang Wang ¹Baofei Jiang ²Jun Cao ³Ting Xu ⁴Chengming Zhou ³Xiangyou Yu ⁵Yi Wang ⁵Yu Xie ¹Lindong Ji ⁶Guangrong Zhou ¹Hao Wen ³Long Ma ⁵Kun Wu⁷

作者信息

1. Department of Hepatobiliary Surgery,The Affiliated Huai''an No.1 People''s Hospital of Nanjing Medical University,Huai''an 223300,China
2. Department of General Surgery,Shanghai Tenth People''s Hospital,Shanghai 200072,China
3. State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia,Xinjiang Medical University,Urumqi 830054,China
4. Hematology Research Laboratory,The Affiliated Huai''an No.1 People''s Hospital of Nanjing Medical University,Huai''an 223300,China
5. Department of Critical Care Medicine,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China
6. Department of Gastrointestinal Surgery,The Affiliated Huai''an No.1 People''s Hospital of Nanjing Medical University,Huai''an 223300,China
7. Department of Gastrointestinal Surgery,The Affiliated Huai''an No.1 People''s Hospital of Nanjing Medical University,Huai''an 223300,China State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia,Xinjiang Medical University,Urumqi 830054,China
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摘要

关键词

NEDD4L/YY1/SLC7A11/ferroptosis/hepatic ischemia-reperfusion injury/ubiquitination

分类

医药卫生

引用本文复制引用

Shaochuang Wang,Baofei Jiang,Jun Cao,Ting Xu,Chengming Zhou,Xiangyou Yu,Yi Wang,Yu Xie,Lindong Ji,Guangrong Zhou,Hao Wen,Long Ma,Kun Wu..Modulation of ferroptosis via YY1-SLC7A11 axis in hepatic ischemia-reperfusion injury pathogenesis[J].Acta Biochimica et Biophysica Sinica,2025,57(9):P.1391-1405,15.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.82360380) （No.82360380）

the Xinjiang Uygur Autonomous Region Tianshan Talent Training Program(No.2024TSYCLJ0047) （No.2024TSYCLJ0047）

the Huai''an Science and Technology Board Natural Science Research Projects(No.HAB202304) （No.HAB202304）

the State Key Laboratory of Pathogenesis,Prevention and Treatment of Central Asian High Incidence Diseases Fund(No.SKL-HIDCA-2020-18). （No.SKL-HIDCA-2020-18）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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