现代中医临床2025，Vol.32Issue(6)：11-15,5.DOI:10.3969/j.issn.2095-6606.2025.06.003
从"气血合脉说"论治恶性肿瘤血液高凝状态
Treatment of hypercoagulable state of blood in malignant tumors based on the theory of qi-blood and vessel coordination
摘要
Abstract
Hypercoagulable state(HCS)can induce abnormal intravascular coagulation,leading to varying degrees of vascular occlusion and venous thromboembolism.The theory of qi-blood and vessel coordination proposed by Wang Qingren elucidates the synergistic relationship between qi and blood,emphasizing that the key to treatment lies in differentiating deficiency and excess patterns of qi and blood.Malignancy-associated hypercoagulability demonstrates close correlation with the blood stasis pattern.The core pathogenesis of malignant HCS lies in toxin impairment of qi-blood with internal blood stasis retention.This condition manifests as root deficiency with superficial excess,where deficiency of vital qi constitutes the fundamental etiology of malignancies,while both cancerous toxins and chemotherapeutic agents directly damage qi and blood.Based on the theory of qi-blood and vessel coordination,two therapeutic approaches are applied for malignant HCS:blood stasis-removing and blood-activating method,as well as qi-tonifying and blood-activating method.The former is exemplified by Wang's Wuzhuyu Decoction(Five Stasis-Resolving Decoction),tailored according to the specific anatomical locations of stasis accumulation.In contrast to the purgative and attacking nature of stasis-removing therapy,the qi-tonifying approach prioritizes supplementation,typically employing the Buyang Huanwu Decoction(Yang-Supplementing and Five-Returning Decoction).This paper elaborates on the management of malignancy-induced hypercoagulability guided by the theory of qi-blood and vessel coordination through clinical case analyses.关键词
恶性肿瘤/血液高凝状态/血瘀证/气血合脉说/理论探讨Key words
malignant tumors/hypercoagulable state/blood stasis/qi-blood and vessel coordination/theoretical discussion分类
医药卫生引用本文复制引用
程诚,刘铸,武佳鑫,刘可心,赵琳,邢彩霞,李潇..从"气血合脉说"论治恶性肿瘤血液高凝状态[J].现代中医临床,2025,32(6):11-15,5.基金项目
北京中医药大学东直门医院人才培养计划项目(No.DZMG-LJRC0002) （No.DZMG-LJRC0002）
中华中医药学会委托课题(No.2024XS-001) （No.2024XS-001）
首都卫生发展科研专项项目(No.2022-4193,No.2024-2-4194) （No.2022-4193,No.2024-2-4194）
