川北医学院学报2025，Vol.40Issue(11)：1390-1393,4.DOI:10.3969/j.issn.1005-3697.2025.11.006
支气管镜肺泡灌洗辅助治疗小儿重症肺炎支原体肺炎疗效及对外周血CRP、PCT水平的影响
Efficacy of bronchoscopic alveolar lavage as an adjuvant therapy for se-vere Mycoplasma pneumoniae pneumonia in children and the impact on peripheral blood CRP and PCT levels
摘要
Abstract
Objective:To investigate the clinical efficacy of bronchoscopic alveolar lavage as an adjuvant therapy for severe Mycoplasma pneumoniae pneumonia(SMPP)in children,and analyze its impact on peripheral blood C-reactive protein(CRP)and procalcitonin(PCT)levels.Methods:A total of 160 children with SMPP were enrolled in the study.Using different treat-ment regimens,they were assigned to the control group and the observation group,80 cases in each group.The groups received conventional treatment and bronchoscopic alveolar lavage assisted conventional treatment,respectively.The duration of clinical symptoms,clinical efficacy,peripheral blood CRP and PCT levels,and complication rate were compared between the two groups.Results:Inter-group comparisons found that the duration of clinical symptoms was shorter in the observation group(P<0.05).The overall clinical effective rate was higher in the observation group(P<0.05).After 2 weeks of treatment,pe-ripheral blood CRP and PCT levels in both groups decreased(P<0.05),and the observation group was lower than the control group(P<0.05).The complication rate in the observation group was lower than that in the control group(3.75%vs.12.50%,P<0.05).Conclusion:Bronchoscopic alveolar lavage as an adjuvant therapy can achieve significant therapeutic effects on SMPP in children.It can shorten the duration of clinical symptoms,lower peripheral blood CRP and PCT levels,and reduce complication risk.关键词
重症肺炎支原体肺炎/支气管镜肺泡灌洗/儿童/疗效/炎症因子/支气管镜检查Key words
Severe Mycoplasma pneumoniae pneumonia/Bronchoscopic alveolar lavage/Child/Efficacy/Inflammatory fac-tor/Bronchoscopy分类
医药卫生引用本文复制引用
郑丹丹,马金海,马小龙,黄捷..支气管镜肺泡灌洗辅助治疗小儿重症肺炎支原体肺炎疗效及对外周血CRP、PCT水平的影响[J].川北医学院学报,2025,40(11):1390-1393,4.基金项目
宁夏自然科学基金项目(2023AAC03550) （2023AAC03550）
