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Cpx-mediated amino acid sensing diversifies gastrointestinal colonization of Klebsiella pneumoniae

Danyang Li Qiucheng Shi Liuqing He Jianhua Luo Huajie Zhu Xiaoting Hua Yunsong Yu Yan Jiang Liang Tao

微生物（英文）2025，Vol.4Issue(2)：181-192,12.

微生物（英文）2025，Vol.4Issue(2)：181-192,12.DOI:10.1002/mlf2.70005

Cpx-mediated amino acid sensing diversifies gastrointestinal colonization of Klebsiella pneumoniae

Danyang Li ¹Qiucheng Shi ²Liuqing He ³Jianhua Luo ³Huajie Zhu ³Xiaoting Hua ²Yunsong Yu ²Yan Jiang ²Liang Tao¹

作者信息

1. College of Life Sciences,Zhejiang University,Hangzhou,China||Key Laboratory of Multi-omics in Infection and Immunity of Zhejiang Province,Center for Infectious Disease Research,School of Medicine,Westlake University,Hangzhou,China||School of Life Sciences,Westlake University,Hangzhou,China||Westlake Laboratory of Life Sciences and Biomedicine,Hangzhou,China
2. Department of Infectious Diseases,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,China
3. Key Laboratory of Multi-omics in Infection and Immunity of Zhejiang Province,Center for Infectious Disease Research,School of Medicine,Westlake University,Hangzhou,China||School of Life Sciences,Westlake University,Hangzhou,China||Westlake Laboratory of Life Sciences and Biomedicine,Hangzhou,China
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摘要

关键词

amino acid sensing/CpxRA/intestinal colonization/Klebsiella pneumoniae/type 3 fimbriae

Key words

amino acid sensing/CpxRA/intestinal colonization/Klebsiella pneumoniae/type 3 fimbriae

引用本文复制引用

Danyang Li,Qiucheng Shi,Liuqing He,Jianhua Luo,Huajie Zhu,Xiaoting Hua,Yunsong Yu,Yan Jiang,Liang Tao..Cpx-mediated amino acid sensing diversifies gastrointestinal colonization of Klebsiella pneumoniae[J].微生物（英文）,2025,4(2):181-192,12.

基金项目

We are grateful for the technical support from the Biomedical Research Core Facility,the High-Performance Computing Center,and the Laboratory Animal Resources Center at Westlake University.This study was partially supported by the National Key R&D Program of China(Grant no.2023YFC2308403),the National Natural Science Foundation of China(Grant no.32430002),the Natural Science Foundation of Zhejiang Province of China(Grant no.LRG25C010001),the Westlake University-Muyuan Joint Re-search Institute(Program no.WU2024MY001),the Westlake Center for Genome Editing(Program no.21200000A992410),the Zhejiang Provincial Key Laboratory Construction Project(2024ZY01026),and the"Pioneer"and"Leading Goose"R&D Program of Zhejiang(Grant no.2024SSYS0029).L.T.also acknowledges support from the Westlake Laboratory of Life Sciences and Biomedicine and the Westlake Education Foundation. （Grant no.2023YFC2308403）

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