日用化学品科学2025，Vol.48Issue(11)：59-67,9.DOI:10.3969/j.issn.1006-7264.2025.11.010
植物提取组合物筛选及其滋养与抗皱紧致功效研究
Screening of plant extract compounds and study on their nourishing and anti-wrinkle tightening effects
张泽奇 1赵梁佑 2赵君 1韩春霞 1周戟 2杨平顺1
作者信息
- 1. 深圳市容大生物科技股份有限公司,广东 深圳 518000
- 2. 云南英格生物技术有限公司,云南 昆明 650506
- 折叠
摘要
Abstract
The nourishing and anti-wrinkle/firming effects of three isoflavone-containing plant extract compositions were evaluated using in vitro cell platforms and 3D skin cell models.The results showed that composition 3 exhibited highest enhancement rate(20.33%)of Collagen I,and had the highest inhibition rate(16.47%)of MMP-1.At a concentration of 2.0%,composition 3 significantly enhanced skin moisture content,ceramide-to-protein ratio,average ceramide chain length,and average fatty acid chain length,with the improvement rates of 187.89%,14.09%,0.83%,and 0.87%,respectively,while the improvement rate of fatty acid/protein ratio was 8.75%.Furthermore,at the same concentration,composition 3 significantly increased collagen fiber content in vivo skin tissue by 166.67%.Overall,composition 3 demonstrated remarkable advantages in skin nourishment and anti-wrinkle/firming effects,particularly in enhancing Collagen I,skin hydration,ceramide and fatty acid content and chain length,increasing collagen fibers,and reducing MMP-1 expression.关键词
黄酮/异黄酮/化品妆功效/滋养/抗皱紧致Key words
flavonoids/isoflavone/cosmetic efficacy/nourishing/anti-wrinkle分类
化学化工引用本文复制引用
张泽奇,赵梁佑,赵君,韩春霞,周戟,杨平顺..植物提取组合物筛选及其滋养与抗皱紧致功效研究[J].日用化学品科学,2025,48(11):59-67,9.
