中风与神经疾病杂志2025，Vol.42Issue(11)：963-967,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0176
超声测量视神经鞘直径在脑死亡中的应用
Application of ultrasonic measurement of optic nerve sheath diameter in assessing brain death
摘要
Abstract
Objective To investigate the application value of ultrasound measurement of optic nerve sheath diam-eter(ONSD)in the assessment of brain death.Methods A total of 124 subjects were enrolled and divided into brain death group with 34 patients,deep coma group with 28 patients,and healthy control group with 62 individuals,and ultra-sound measurement of ONSD was performed for all three groups.A Spearman correlation analysis was used to investigate the correlation of brain death with ONSD and baseline characteristics.Univariate and multivariate Logistic regression analyses were used to identify the independent predictive value of ONSD for brain death.The receiver operating character-istic(ROC)curve was plotted to determine the optimal cut-off value of ONSD and evaluate its diagnostic efficacy.Results The Spearman correlation analysis showed a significant positive correlation between brain death and ONSD(r=0.825,P<0.001).The multivariate Logistic regression analysis confirmed that ONSD was an independent predictive fac-tor for brain death(odds ratio=70.874,P<0.05,Nagelkerke R2=0.739,Hosmer-Lemeshow test P=0.786).ONSD had an area under the ROC curve(AUC)of 0.939(95%CI 88.3‒99.4)in the brain death group and the deep coma group,with an optimal cut-off value of 6.005 mm,a sensitivity of 97.1%,a specificity of 78.6%,a positive predictive value of 84.6%,and a negative predictive value of 95.7%.Conclusion Ultrasound measurement of ONSD has an important clinical application value in the assessment of brain death.关键词
脑死亡/视神经鞘直径/无创Key words
Brain death/Optic nerve sheath diameter/Noninvasive measurement分类
医药卫生引用本文复制引用
白丽杨,李小丹,王思博,张洁,李聪,王丽娟..超声测量视神经鞘直径在脑死亡中的应用[J].中风与神经疾病杂志,2025,42(11):963-967,5.基金项目
吉林省自然科学基金(YDZJ202501ZYTS019) （YDZJ202501ZYTS019）
吉林省医药卫生人才专项(JLSRCZX2025-041) （JLSRCZX2025-041）
