中风与神经疾病杂志2025，Vol.42Issue(11)：1012-1016,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0185
卵圆孔未闭相关隐源性卒中穿支动脉梗死患者的临床特征及超声心动图改变
Clinical features and echocardiographic changes of cryptogenic perforator infarction patients with patent foramen ovale
摘要
Abstract
Objective We sought to investigate the clinical characteristics and echocardiographic changes of cryptogenic perforator infarction(PI)patient with patent foramen ovale(PFO).Methods From Jan 2015 to Dec 2023,patients diagnosed with cryptogenic stroke were retrospectively included in our study.All patients received transthoracic echocardiography(TTE)and transcranial Doppler(TCD).PFO was diagnosed by the bubble test of TCD.Comparisons of clinical features and TTE findings were performed firstly in PI patients,between PFO and non-PFO,and then in patients with PFO,between PI and cortical infarction(CI).Results A total of 251 patients were retrospectively analyzed.PFO was detected in 104 patients,of those,40.4%(42/104)had pure PI(PFO-PI)and 59.6%(62/104)had CI(PFO-CI).In patients without PFO,30.6%(45/147)had pure PI(non-PFO-PI).Compared with non-PFO-PI,PFO-PI associated with a higher proportion of vertebrobasilar circulation infarctions(VCI)(47.6%vs 17.8%,P=0.003),lower mean value of left ventricle end-diastolic diameters(LVEDd)(47.3 mm vs 49.8 mm,P=0.037)and lower peak E-wave velocity(62.6 cm/s vs 70.8 cm/s,P=0.015).In PFO patients,PFO-PI was detected with a lower mean value of aorta root diameters(32.5 mm,P=0.011)and lower mean value of LVEDd(47.3 mm,P=0.045)than PFO-CI(34.5 mm and 49.4 mm,respectively).Conclusion Higher proportion of VCI was found in PFO-PI.Lower LVEDd,lower Em and without aortic root dilatation were three echocardiographic features associated with PFO-PI in cryogenic PI patients.关键词
经胸超声心动图检查/隐源性卒中/穿支动脉梗死/卵圆孔未闭Key words
Transthoracic echocardiography/Cryptogenic stroke/Perforator infarction/Patent foramen ovale分类
医药卫生引用本文复制引用
张慧,唐海燕,吴斐,余纯,董强,曹文杰..卵圆孔未闭相关隐源性卒中穿支动脉梗死患者的临床特征及超声心动图改变[J].中风与神经疾病杂志,2025,42(11):1012-1016,5.基金项目
四大慢病重大专项资助(2023ZD0505400) （2023ZD0505400）
