协和医学杂志2025，Vol.16Issue(6)：1371-1375,5.DOI:10.12290/xhyxzz.2025-0782
炎症性肠病治疗药物的血栓风险及预防策略
Risk of Drug-induced Thrombosis in Patients with Inflammatory Bowel Disease and Preventive Strategies
摘要
Abstract
Inflammatory bowel disease(IBD),a chronic inflammatory condition of the gastrointestinal tract,is associated with a significantly increased risk of both venous and arterial thromboembolism.Common risk factors for thrombosis include disease activity,surgery,older age,central venous catheterization,etc.However,thrombotic events related to pharmacological treatment are often under-recognized,despite their po-tential for severe consequences.With the rapid expansion of therapeutic options for IBD in recent years,it has become increasingly important to acknowledge that different agents carry varying levels of thrombotic risk.This review summarizes current evidence on the thrombotic risks associated with IBD therapies and outlines preven-tive strategies,aiming to optimize the thrombosis risk management and reduce treatment-related thrombotic events in IBD patients.关键词
炎症性肠病/治疗药物/血栓Key words
inflammatory bowel disease/therapeutic drugs/thrombosis分类
医药卫生引用本文复制引用
刘亚文,魏宇歌,吴作艳,高小毛,杨红..炎症性肠病治疗药物的血栓风险及预防策略[J].协和医学杂志,2025,16(6):1371-1375,5.基金项目
国家重点研发计划(2023YFC2507302) （2023YFC2507302）
北京市自然科学基金(7252113) （7252113）
国家自然科学基金(82570621)National Key Research and Development Program of China(2023YFC2507302) （82570621）
Beijing Natural Science Founda-tion(7252113) （7252113）
National Natural Science Foundation of China(82570621) （82570621）
