中国实验动物学报2025，Vol.33Issue(10)：1492-1503,12.DOI:10.3969/j.issn.1005-4847.2025.10.010
COPD相关共病动物模型研究进展
Research progress in animal models of COPD related comorbidity
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a common but preventable and treatable lung disease characterized by persistent airflow limitation.Comorbidities related to COPD have recently received widespread attention because of their serious effects on the quality of life and prognosis of patients,and their role in promoting the malignant development of COPD.Experimental animal models provide a key for studying the pathogenesis of COPD and its related comorbidities and for exploring effective treatment methods.This review summarizes the modeling methods and research progress into experimental animal models of COPD-related comorbidities,to provide references and guidance for future clinical research and screening of animal models of related comorbidities.关键词
慢性阻塞性肺疾病/相关共病/动物模型/中医模型Key words
chronic obstructive pulmonary disease/related comorbidity/animal model/TCM model分类
生物科学引用本文复制引用
崔钰伟,臧凝子,刘勇明,庞立健..COPD相关共病动物模型研究进展[J].中国实验动物学报,2025,33(10):1492-1503,12.基金项目
国家自然科学基金面上项目(82474608),青创团队项目(2024-JYTCB-081),辽宁中医药大学"中医藏象理论及应用教育部重点实验室"开放基金(zyzx2210),中国博士后科学基金项目(2022MD723797).Funded by General Program of the National Natural Science Foundation of China(82474608),Youth Innovation Team Project(2024-JYTCB-081),Open Fund of Liaoning University of Traditional Chinese Medicine"Ministry of Education Key Laboratory of Traditional Chinese Medicine Visceral Theory and Application"(zyzx2210),China Postdoctoral Science Foundation Project(2022MD723797). （82474608）
