中国实用内科杂志2025，Vol.45Issue(11)：917-920,4.DOI:10.19538/j.nk2025110106
运动"多靶点、全路径"改善心血管代谢性疾病
Exercise for cardiometabolic diseases:multi-target and comprehensive pathway benefits
摘要
Abstract
Cardiometabolic diseases(CMD)have emerged as a major global public health challenge,whose pathogenesis is complicated,including insulin resistance,chronic inflammation,and vascular dysfunction.Exercise,as a non-pharmacological intervention with the advantage of multiple targets,has demonstrated significant efficacy in preventing and managing CMD in a comprehensive pathway.This article elaborates on the physiological mechanisms underlying exercise-mediated CMD and the clinical efficacy of various exercise modalities,and outlines principles of developing individualized exercise prescriptions guided by cardiopulmonary exercise testing(CPET)and implementation strategies.It also explores real-world challenges in adherence,healthcare resource distribution,and precision management.Based on the recent advances in digital health technologies and precision rehabilitation,it is proposed to establish a multidiscipline-integrated,technology-enabled,and policy-supported comprehensive-pathway closed-loop management framework.Exercise is not only a component of a healthy lifestyle but also an effective therapeutic strategy with"multi-target and comprehensive pathway"benefits for improving outcomes in patients with CMD.It should be further established as a standard intervention pathway in prevention and control of chronic diseases.关键词
心血管代谢性疾病/运动干预/心肺运动试验/个体化处方/慢病管理Key words
cardiometabolic diseases/exercise intervention/cardiopulmonary exercise testing/individualized prescription/chronic disease management分类
医药卫生引用本文复制引用
周乐群,沈涛,唐熠达..运动"多靶点、全路径"改善心血管代谢性疾病[J].中国实用内科杂志,2025,45(11):917-920,4.基金项目
国家自然科学基金专项(T2541009) （T2541009）
