中国医学伦理学2025,Vol.38Issue(11):1398-1408,11.DOI:10.12026/j.issn.1001-8565.2025.11.04
2016-2024年人源类器官伦理国际研究的可视化分析
A visual analysis of international research on the ethics of human organoids from 2016 to 2024
摘要
Abstract
With the rapid advancement of science and technology,human organoid technology has demonstrated immense potential in medical research and treatment,but it has also raised complex ethical issues.Ethical research on human organoid has gradually become a hot field of concern in the international academic community.Taking 262 papers from the Web of Science core database from 2016 to 2024 as a sample,this paper employed bibliometrics and visualization methods to analyze the hotspots and evolutionary trends of international research on the ethics of human organoid.The results showed that international research on the ethics of human organoid exhibited a significant growth trend,going through three phases:a slow accumulation period,a sustained explosion period,and a circuitous growth period.The primary research forces were concentrated in the United States,China,the United Kingdom,and Italy,with China gradually emerging in this domain.The research hotspots were mainly focused on the following aspects.The first was the research of classical ethical issues,encompassing an overview of the overall ethical issues in the research and application of human organoid technology,and the ethical issues of organoid biobanks.The second was the new challenges in ethical issues,including the moral status and ethical governance of brain organoids,embryoid bodies,and gonadal organoids.The third was ethical issues arising from cross-disciplinary applications,covering the ethical challenges posed by chimeras formed through transplanting human brain organoid into non-human animals and hybrids created by connecting human brain organoid with artificial intelligence(AI),robots,and other non-biological entities.As technology continues to advance,the complexity and importance of ethical issues related to human organoid will persistently increase,and research in this field will continue to deepen and expand in the future.关键词
人源类器官伦理/科技伦理/道德地位/伦理治理Key words
ethics of human organoid/science and technology ethics/moral status/ethical governance分类
医药卫生引用本文复制引用
罗会宇,罗雅君,陶应时..2016-2024年人源类器官伦理国际研究的可视化分析[J].中国医学伦理学,2025,38(11):1398-1408,11.基金项目
国家社会科学基金一般项目"人源类器官研究和应用中的伦理问题"(22BZX130) (22BZX130)
2023年度河南省本科高校青年骨干教师培养计划项目"河南省科技伦理治理问题研究"(2023GGJS105) (2023GGJS105)
河南省软科学项目"河南省多元共治科技伦理治理体制建设研究"(242400410004) (242400410004)