中国医学伦理学2025，Vol.38Issue(11)：1425-1430,6.DOI:10.12026/j.issn.1001-8565.2025.11.07
植入前多基因检测的伦理问题探究
Exploration of ethical issues in preimplantation polygenic testing
摘要
Abstract
Preimplantation polygenic testing,as a frontier technology in assisted reproduction,provides a new way to prevent genetic diseases and reduce birth defects.However,it may also trigger a series of ethical issues.Combined with the research progress of preimplantation polygenic testing,this paper explored the ethical issues that may be caused by this technology,including the risks and uncertain benefits for future offspring and the challenges of informed consent,the dilemmas of autonomous decision-making and genetic responsibility of prospective parents,as well as social risks such as the distortion of the view of life and health inequities.Given the technical safety issues and ethical challenges posed by preimplantation polygenic testing,it was proposed to revise the regulations related to preimplantation genetic testing,as well as improve the ethical review of preimplantation polygenic testing,genetic counseling services,and public education on genetic science and genetic ethics.These ethical countermeasures aim to prevent and mitigate risks and ensure that technology truly benefits human society.关键词
植入前基因检测/多基因评分/多基因病Key words
preimplantation genetic testing/polygenic risk score/polygenic disease分类
医药卫生引用本文复制引用
于泽慧,梁立智..植入前多基因检测的伦理问题探究[J].中国医学伦理学,2025,38(11):1425-1430,6.基金项目
北京市社会科学基金一般项目"人体基因检测在中国应用的伦理规制研究"(19ZXB005) （19ZXB005）
