中国中西医结合影像学杂志2025，Vol.23Issue(6)：711-716,6.DOI:10.3969/j.issn.1672-0512.2025.06.008
基于HRCT小气道参数探讨咳喘停穴位贴敷治疗支气管哮喘的机制
Exploration of efficacy mechanism of Kechuanting acupoint application on patients with bronchial asthma based on HRCT small airway parameters
摘要
Abstract
Objective:To explore the mechanism of therapeutic effect of Kechuanting acupoint application on patients with chronic asthma based on HRCT small airway parameters.Methods:Thirty-four patients with chronic persistent asthma were randomly divided into a Western medicine group(16 cases)and a Western medicine combined with acupoint application group(18 cases).Both groups were treated with low-dose budesonide and formoterol powder inhalation,and the combined group was additionally treated with Kechuanting acupoint application.Both groups underwent asthma control questionnaire(ACQ-7)score and chest HRCT examination on the day of enrollment and within one week after the end of treatment,respectively.The changes of ACQ-7 score and HRCT small airway parameters were compared between and within groups before and after treatment.The quantitative indicators of HRCT small airway parameters included wall thickness(WT),airway diameter,ratio of airway wall thickness to cross-sectional diameter(TDR),and ratio of bronchial wall area to total cross-sectional area(WA%).Qualitative indicators included end-inspiratory bronchiolitis and end-expiratory air retention signs.Results:There were no statistically significant differences in gender,age,BMI,disease duration,ACQ-7 score or HRCT small airway parameters before treatment between the two groups(all P>0.05).After treatment,there were no statistically significant differences in ACQ-7 score,small airway diameter,end-inspiratory bronchiolitis or end-expiratory air retention signs between the two groups(all P>0.05).WT,TDR and WA%in the combined group were lower than those in the Western medicine group(all P<0.01).Compared with before treatment,there were no statistically significant differences in ACQ-7 score,WT,TDR or WA%in the Western medicine group after treatment(all P>0.05),while ACQ-7 score,WT,TDR and WA%in the combined group decreased after treatment(all P<0.05).The changes in WT,TDR and WA%within the two groups before and after treatment were statistically significant(all P<0.05).Conclusions:HRCT small airway parameters can be used to evaluate the efficacy of asthma,and it has been confirmed from the perspective of imaging that Kechuanting acupoint application in the treatment of asthma can improve small airway inflammation and dilate the airway.关键词
哮喘/体层摄影术,X线计算机/小气道/穴位贴敷/疗效Key words
Asthma/Tomography,X-ray computed/Small airway/Acupoint application/Efficacy引用本文复制引用
凌丽芳,曾亮,王兵,徐静,龚晓燕,赵舒梅,刘兰英..基于HRCT小气道参数探讨咳喘停穴位贴敷治疗支气管哮喘的机制[J].中国中西医结合影像学杂志,2025,23(6):711-716,6.基金项目
江苏省高等教育教改研究项目(2023JSJG014) （2023JSJG014）
江苏省中医药管理局科技发展项目(ZT202205) （ZT202205）
江苏省中医院科技项目(Y21025) （Y21025）
江苏省中医院科主任学术提升专项项目(Y2022ZR21). （Y2022ZR21）
