北京中医药2025，Vol.44Issue(10)：1255-1258,4.DOI:10.16025/j.1674-1307.2025.10.006
归苓汤联合火针治疗神经性皮炎临床疗效观察
Clinical observation of Guiling Decoction combined with fire needle therapy in treatment of neurodermatitis
摘要
Abstract
Objective To evaluate the clinical efficacy and safety of Guiling Decoction combined with fire needle therapy in the treatment of neurodermatitis(ND).Methods A total of 120 ND patients who visited the Department of Dermatology and Venereology of Beijing University of Chinese Medicine Third Affiliated Hospital from October 2023 to May 2024 were enrolled and randomly assigned into an observation group and a control group(60 patients each)using a random number table.Both groups received topical application of Vaseline twice daily.The control group received oral Guiling Decoction,while the observation group was treated with oral Guiling Decoction combined with fire needle therapy for 4 weeks.Clinical efficacy,skin lesion scores,Visual Analog Scale(VAS)for pruritus,Athens Insomnia Scale(AIS)scores,VAS for accompanying symptoms,safety,and recurrence rates were compared between the two groups before and after treatment.Results The total effective rate in the observation group was higher than that in the control group(P<0.05).After 4 weeks of treatment,VAS scores for pruritus,AIS scores,and VAS scores for accompanying symptoms decreased in both groups compared with baseline(P<0.05),with the observation group showing greater improvement in VAS scores for pruritus and AIS scores than the control group(P<0.05).Skin lesion scores at weeks 2 and 4 were lower than baseline in both groups(P<0.05),and the observation group had lower scores than the control group(P<0.05).No drug-related adverse events occurred in either group,and scabbing was observed after fire needle therapy,which resolved within 3-10 days.At 3-month follow-up,1 patient in the observation group relapsed(1.79%),and 4 patients in the control group relapsed(9.09%),with no statistically significant difference in recurrence rate between the two groups(P>0.05).Conclusion Guiling Decoction combined with fire needle therapy can improve the clinical efficacy in treating ND and is safe.关键词
归苓汤/火针/神经性皮炎Key words
Guiling Decoction/fire needle therapy/neurodermatitis引用本文复制引用
张萱,孙占学,张莉莉,马胜南..归苓汤联合火针治疗神经性皮炎临床疗效观察[J].北京中医药,2025,44(10):1255-1258,4.基金项目
国家中医药管理局全国中医临床优秀人才研修项目(国中医药人教函[2022]1号) （国中医药人教函[2022]1号）
北京中医药大学"岐黄英才·名医培育计划"(Y2023A05) （Y2023A05）
2024年北京中医药大学研究生自主科研课题(ZJKT2024057) （ZJKT2024057）
