分析测试学报2025，Vol.44Issue(12)：2507-2515,9.DOI:10.12452/j.fxcsxb.250301134
基于MWCNTs/GOx/LIG电极的葡萄糖电化学传感研究
Study on Electrochemical Glucose Sensing Based on MWCNTs/GOx/LIG Electrodes
摘要
Abstract
Diabetes mellitus is a major challenge in the global public health field,and its early diag-nosis and dynamic monitoring are of great significance for disease management.In this paper,a glu-cose sensor based on laser-induced graphene(LIG)electrode modified by carbon nanotube-enzyme complex was constructed.A 3D patterned graphene three-electrode system was prepared by laser di-rect writing technology.The aminated multi-walled carbon nanotubes(N-MWCNTs)and glucose oxi-dase(GOx)were covalently bound and modified to the surface of the working area of the LIG electrode by glutaraldehyde.The current response of glucose on the composite electrode was determined by chronoamperometry.The results showed that the cross-linking of N-MWCNTs could effectively im-prove the sensitivity of glucose sensors.The prepared composite electrode had a good current re-sponse to glucose solution in the range of 0.5×10-6-5×10-3 mol/L concentration,and the detection limit was 0.5×10-7 mol/L.The sensor exhibits high sensitivity,good precision,repeatability,selec-tivity,stability and flexibility,and can be used for glucose detection in biological samples such as serum,sweat,urine,etc.The preparation of the LIG immobilized enzyme electrode is simple,green and low-cost,and shows broad application prospects in portable blood glucose detection.关键词
葡萄糖/电化学传感器/葡萄糖氧化酶/多壁碳纳米管/激光诱导石墨烯Key words
glucose/electrochemical sensor/glucose oxidase/multi-walled carbon nanotubes/laser-induced graphene分类
化学化工引用本文复制引用
陈依伊,周宇辰,罗萍,陈菀淳,李艳霞..基于MWCNTs/GOx/LIG电极的葡萄糖电化学传感研究[J].分析测试学报,2025,44(12):2507-2515,9.基金项目
福建省自然科学基金项目(2024J011175) （2024J011175）
国家级大学生创新创业训练计划项目(202410395008) （202410395008）
