杭州师范大学学报（自然科学版）2025，Vol.24Issue(6)：571-576,6.DOI:10.19926/j.cnki.issn.1674-232X.2024.04.261
一种D-π-A构型的四苯乙烯衍生物的合成及细胞成像研究
Synthesis and Cell Imaging Study of a D-π-A Tetraphenylethene Derivative
摘要
Abstract
To achieve specific targeting and recognition of mitochondria in living cells,a compound XC with a D-π-A structure was designed and synthesized using tetraphenylethylene and pyridinium salt as building blocks.UV-visible absorption and fluorescence emission spectra demonstrated that the compound exhibited good chemical stability and aggregation-induced emission(AIE)characteristics.Further cytotoxicity and confocal microscopy imaging experiments indicated that compound XC had low cytotoxicity,good biocompatibility,and the ability to specifically target mitochondria.These results confirm that compound XC is suitable for mitochondrial imaging studies in cells.关键词
四苯乙烯/聚集诱导发光/细胞成像/荧光性质Key words
tetraphenylethylene/aggregation-induced emission/cell imaging/fluorescent properties分类
化学化工引用本文复制引用
张思晨,汪捷,王志宇,张雪,胡磊,王慧..一种D-π-A构型的四苯乙烯衍生物的合成及细胞成像研究[J].杭州师范大学学报（自然科学版）,2025,24(6):571-576,6.基金项目
安徽省高校自然科学研究项目(2023AH051762,2023AH051747) （2023AH051762,2023AH051747）
皖南医学院大学生科研资助基金项目(WK2024XS38). （WK2024XS38）
