陕西中医2025，Vol.46Issue(12)：1628-1631,1641,5.DOI:10.3969/j.issn.1000-7369.2025.12.008
滋癸益经汤联合激素治疗对脾肾阳虚型卵巢早衰患者相关激素水平及预后的影响
Effect of Zigui Yijing decoction combined with hormone therapy on hormone levels and prognosis in premature ovarian failure of spleen-kidney yang deficiency type
摘要
Abstract
Objective:The study investigates the effects of Zigui Yijing decoction combined with hormones on hormone levels and prognosis in premature ovarian failure of the spleen-kidney yang deficiency type.Methods:A total of 80 patients with ovarian failure of spleen and kidney yang deficiency were selected and divided into control group and study group,each with 40 cases,and the patients in the control group received hormone therapy,and the study group received hormone combined with Zigui Yijing decoction for a total of 3 months.Before and after treatment,we compared the TCM syndrome score,ovarian function,serum levels of follicle stimulating hormone,testosterone and luteinizing hormone,the efficacy of treatment,menstrual resurgence rate after treatment and adverse reactions.Results:For the total effective rate,the study group was higher than control group(95.00%vs 75.00%,P<0.05).After treatment,the TCM syndrome scores and serum FSH,LH and T hormone levels of the control groups were de-creased(P<0.05),and all strongly higher than the study group(P<0.05).The ovarian volume,the number of fol-licles and peak systolic flow velocity of ovarian blood flow were increased in the two groups(P<0.05),and the ovar-ian functions was higher in the study group(P<0.05).After treatment,the proportion of patients in the study group who had two menstrual cramps>two times within six months(45.00%vs 15.00%,P<0.05),but there was no significant difference in the overall incidence of adverse reactions between the two groups during treatment(40.00%vs 32.50%,P>0.05).Conclusion:Zigui Yijing decoction has a significant clinical effect on premature ovarian failure with spleen-kidney yang deficiency,which can significantly improve the level of sex hormones in patients,improve o-varian function and menstrual resurgence rate in patients,and is safe and effective.关键词
卵巢早衰/滋癸益经汤/脾肾阳虚/激素/月经/戊酸雌二醇Key words
Premature ovarian failure/Zigui Yijing decoction/Spleen-kidney yang deficiency/Hormone/Men-struation/Estradiol valerate分类
医药卫生引用本文复制引用
周欣,王永莉,汪妍..滋癸益经汤联合激素治疗对脾肾阳虚型卵巢早衰患者相关激素水平及预后的影响[J].陕西中医,2025,46(12):1628-1631,1641,5.基金项目
国家自然科学基金资助项目(82305147) （82305147）
