山西中医药大学学报2025，Vol.26Issue(9)：1003-1008,6.DOI:10.19763/j.cnki.2096-7403.2025.09.10
基于温肾健脾法调节甲状腺-肠轴治疗桥本甲状腺炎
Treatment of Hashimoto's thyroiditis by regulating the thyroid-gut axis through the method of warming the kidney and strengthening the spleen
摘要
Abstract
Hashimoto's thyroiditis(HT)is an immune-mediated disease involving T and B lymphocytes.In the ad-vanced stages of the disease,it often leads to hypothyroidism,causing dysfunction in the metabolic,cardiovascular,ner-vous,reproductive,digestive,and hematological systems,and frequently coexists with intestinal diseases.Numerous stud-ies have demonstrated significant differences in the intestinal flora between HT patients and healthy individuals.Alteration of intestinal flora can lead to thyroid immune dysfunction,resulting in elevated thyroid-related antibodies,which are cru-cial factors in the onset and progression of HT.In traditional Chinese medicine,HT falls under the category of"goiter".When complicated by hypothyroidism,it is often classified as a syndrome of spleen-kidney Yang deficiency.On the basis of Yang deficiency,there is an imbalance in fluid metabolism,leading to the internal production of phlegm and dampness,which combines with Qi and blood,accumulates in the neck,and disrupts the flow of Qi and blood between the upper and lower body,resulting in Qi stagnation,phlegm and blood stasis.Clinically,patients predominantly exhibit Yang deficiency symptoms such as aversion to cold and cold limbs,fatigue,pale complexion,edema,soreness and weakness in the lower back and knees,and myxedema,accompanied by intestinal symptoms such as constipation or diarrhea.Therefore,we fur-ther explore the interrelationship between the thyroid gland and the intestine,analyze the pathogenesis from the perspectives of modern medicine as well as TCM theories such as Yin-Yang and Meridian Theories,and conclude that the fundamental pathogenesis of both conditions is spleen-kidney Yang deficiency.Therefore,based on syndrome differentiation and treat-ment,the method of warming the kidney and strengthening the spleen is used to encourage the whole body Yang Qi,regu-late the thyroid-intestinal axis,promote the Qi transformation function of the viscera,and restore the normal peristalsis of the intestine.关键词
桥本甲状腺炎/甲状腺-肠轴/温肾健脾法Key words
HT/thyroid-gut axis/warming the kidney and strengthening the spleen分类
医药卫生引用本文复制引用
彭晓芳,于佳乐,巴帅杰,张诚,杨青,党翔,董慧杰,党毓起..基于温肾健脾法调节甲状腺-肠轴治疗桥本甲状腺炎[J].山西中医药大学学报,2025,26(9):1003-1008,6.基金项目
宁夏回族自治区卫生健康系统科研项目(2022-NWKY-085) （2022-NWKY-085）
