西北农业学报2025，Vol.34Issue(11)：1975-1982,8.DOI:10.7606/j.issn.1004-1389.2025.11.001
5种水产药物对斑重唇鱼仔鱼的急性毒性及安全评价
Acute Toxicity and Safe Concentrations of Five Aquatic Drugs for Larvae of Diptychus maculatus Steindachner
摘要
Abstract
This study conducted 96-hour acute toxicity tests on Diptychus maculates Steindachner(mean body mass:96.23 mg±6.03 mg)to determine the safety thresholds for commonly used aqua-culture drugs:formaldehyde,sodium chloride,povidone-iodine,benzalkonium bromide and methylene blue.These therapeutics are frequently applied in the treatment of bacterial and parasitic infections,gill rot,dermatosis,and saprolegniasis.The 96-h median lethal concentration(LC50)values were 65.05 mg/L(moderate toxicity)for formaldehyde,11 590.12 mg/L(low toxicity)for sodium chlo-ride,28.60 mg/L(high toxicity)for povidone-iodine,1.10 mg/L(extreme toxicity)for benzalkoni-um bromide,and 18.74 mg/L(high toxicity)for methylene blue.The corresponding safety concen-trations were calculated as 13.06 mg/L,3 412.65 mg/L,7.25 mg/L,0.20 mg/L and 4.79 mg/L,re-spectively.Sensitivity of D.maculatus larvae to these drugs decreased in the following order:benza-lkonium bromide＞methylene blue＞povidone-iodine＞formaldehyde＞sodium chloride.Among these,benzalkonium bromide exhibited the highest toxicity,followed by methylene blue and povidone-iodine,while formaldehyde and sodium chloride showed comparatively lower toxicity.关键词
水产药物/斑重唇鱼/急性毒性/安全浓度Key words
Aquatic drugs/Diptychus maculatus Steindachner/Acute toxicity/Safe concentrations引用本文复制引用
张涛,胡江伟,米乃瓦尔·木依提,沙文军,高广扩,杨博文,蔡林钢,牛建功..5种水产药物对斑重唇鱼仔鱼的急性毒性及安全评价[J].西北农业学报,2025,34(11):1975-1982,8.基金项目
新疆自然科学基金(2023D01A114). Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2023D01A114). （2023D01A114）
