新医学2025，Vol.56Issue(11)：1091-1099,9.DOI:10.12464/j.issn.0253-9802.2025-0289
基于关联规则的脑小血管病患者主要临床症状及影响因素分析
Analysis of primary clinical symptoms and influencing factors in patients with cerebral small vessel disease based on association rules
摘要
Abstract
Objective To explore the rules of association and factors influencing the main symptoms of hospitalized patients with cerebral small vessel disease.Methods Clinical data of 240 patients with cerebral small vessel disease who were hospitalized in the Department of Neurology,the Third Affiliated Hospital of Sun Yat-sen University from January 2020 to June 2024 were retrospectively analyzed.The main symptoms were extracted,and the Apriori algorithm was used for symptom association rule analysis.Binary logistic regression analysis was then performed to identify the influencing factors of the main symptoms.Results The five main symptoms associated with cerebral small vessel disease were dizziness(69.6%),poor sleep quality(44.5%),headache(28.7%),sensory abnormalities(23.3%),and limb weakness(22.1%),respectively.Association rule analysis revealed that dizziness,poor sleep quality,headache,unsteady gait,nausea,vomiting,limb weakness,and chest tightness were mutually associated.Logistic association analysis demonstrated that age≥75(OR=3.304)was an independent risk factor for dizziness.Elevated serum amylase(OR=1.013),chest tightness(OR=4.948),and the presence of malnutrition risk(OR=4.477)were the risk factors for poor sleep quality.Poor sleep quality(OR=1.979)was an independent risk factor for headache(P＜0.05).Conclusions Patients with cerebral small vessel disease present with a complex and diverse array of symptoms that are highly interconnected.Greater attention should be paid to dizziness in elderly patients,while also focusing on sleep issues in those at risk of malnutrition or with elevated amylase levels,as well as the correlations between sleep and symptoms such as chest tightness and headache.Comprehensive symptom management must be strengthened.关键词
脑小血管病/症状管理/关联规则/头晕/睡眠质量/头痛Key words
Cerebral small vessel disease/Symptom management/Association rules/Dizziness/Sleep quality/Headache引用本文复制引用
杨倩,樊萍,阮恒芳,左梦云,陈露,张利峰..基于关联规则的脑小血管病患者主要临床症状及影响因素分析[J].新医学,2025,56(11):1091-1099,9.基金项目
广东省卫生健康委员会卫生健康适宜技术推广项目(202405111023292806) （202405111023292806）
中山大学附属第三医院面上项目(2024HLMS01) （2024HLMS01）
