中国输血杂志2025，Vol.38Issue(11)：1529-1534,6.DOI:10.13303/j.cjbt.issn.1004-549x.2025.11.008
华北地区血站实验室检测前溶血和乳糜血标本管理情况调查
Investigation on the management of hemolytic and lipemic samples in the preanalytical phase in blood station laboratories in North China
孙婧 1葛红卫 1刘正敏 1秦倩倩 1韩卫 2潘彤 3焦东丽 4董效兰 5王瑞1
作者信息
- 1. 北京市红十字血液中心,北京 100088
- 2. 河北省血液中心,河北 石家庄 050000
- 3. 天津市血液中心,天津 300074
- 4. 山西省血液中心,山西 太原 030012
- 5. 内蒙古自治区血液中心,内蒙古 呼和浩特 010050
- 折叠
摘要
Abstract
Objective To investigate the assessment criteria and subsequent handling practices of hemolytic and lipemic blood samples before testing in blood screening laboratories in North China,and to provide data to support the stand-ardization of their management in blood station laboratories.Methods Data on the preanalytical management of hemolytic and lipemic samples from 38 laboratories were collected.The details of management on the criteria and verificatioon for as-sessment,the assessment methods,and subsequent handling procedures of hemolytic and lipemic samples in blood station laboratories were analyzed.Results 1)All 38 blood station laboratories monitored serological and nucleic acid samples for hemolysis and lipemia in pre-analytical phase.2)The criteria and methods for assessing hemolytic and lipemic samples var-ied among the laboratories of the 38 blood stations.15 laboratories(39.47%)followed manufacturer's instructions,9 labo-ratories(23.68%)formulated their own criteria,and 14 laboratories(36.84%)referred to the criteria of other laborato-ries.16 laboratories(42.11%)verified the criteria for assessing hemolytic and lipemic samples,with significant variations in verification rate across laboratories from different regions(P<0.05).For the assessment methods,visual inspection was used by 28 laboratories(73.68%)for hemolytic samples and by 27 laboratories(71.05%)for lipemic samples;the colori-metric card method was used by 10 laboratories(26.32%)for assessing both hemolytic and lipemic samples;the instrumen-tal method was used by 1 laboratory(2.63%)for assessing lipemic samples.3)The handling procedures for hemolytic and lipemic samples varied significantly and followed a gradient distribution pattern among 38 laboratories(including accepting samples for testing,accepting samples for concession testing,re-collecting samples,and rejecting samples and halting tes-ting).With increasing severity of hemolysis and lipemia,more laboratories halted testing,and relatively fewer laboratories accepted samples for normal testing.5 laboratories(13.16%)applied different handling procedures on serological and nu-cleic acid samples.Conclusion This survey provides a reference and basis for analyzing gaps in the management of hemo-lytic and lipemic samples during the preanalyical phase in blood station laboratories in North China.It enables laboratories to identify the problems and deficiencies in the management of hemolytic and lipemic samples,to ensure preanalytical sam-ples quality meets the established requirements,and to lay a foundation for promoting the homogenization and standardization of the regional sample quality management mode.关键词
溶血/乳糜血/华北地区/检测前处理Key words
hemolytic blood/lipemic blood/the North China region/preanalytical process分类
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孙婧,葛红卫,刘正敏,秦倩倩,韩卫,潘彤,焦东丽,董效兰,王瑞..华北地区血站实验室检测前溶血和乳糜血标本管理情况调查[J].中国输血杂志,2025,38(11):1529-1534,6.
