中国医院用药评价与分析2025，Vol.25Issue(11)：1281-1285,1290,6.DOI:10.14009/j.issn.1672-2124.2025.11.001
Core GRADE方法学体系:GRADE证据质量评价与指南制定核心方法
Core GRADE Methodological System:Core Approach for Evidence Quality Assessment and Guideline Development in GRADE
摘要
Abstract
To address the issues of increasing operational complexity and methodological inconsistencies encountered during the application of the Grading of Recommendations Assessment,Development and Evaluation(GRADE)framework.It is necessaiy to establish a more concise and efficient evidence quality assessment system,and the Core GRADE methodological system is developed.The Core GRADE methodological system provides methods for constructing clinical questions,evaluating evidence quality(including determining evidence quality objectives,and assessing imprecision,inconsistency,risk of bias,indirectness,and publication bias),and formulating recommendations from evidence.Meanwhile,the Core GRADE methodological system recommends to use summary of finding tables to summarize evidence and introduces the core methods for guideline developers and health technology assessment professionals in translating evidence into recommendations or decisions.The Core GRADE methodological system provides a more efficient and practical approach for evidence quality assessment and recommendation formulation in systematic reviews,clinical guidelines,and health technology assessments.关键词
GRADE/系统评价/临床指南/卫生技术评估/证据质量/推荐意见Key words
GRADE/Systematic review/Clinical guideline/Health technology assessment/Evidence quality/Recommendation分类
医药卫生引用本文复制引用
曾力楠,程晓,陈婧婧,张伶俐,贺彤,李海龙,邹锟,杨春松,刁莎,刘丹,陈哲,倪晓凤..Core GRADE方法学体系:GRADE证据质量评价与指南制定核心方法[J].中国医院用药评价与分析,2025,25(11):1281-1285,1290,6.基金项目
国家自然科学基金面上项目(No.72474148) （No.72474148）
