中国卒中杂志2025，Vol.20Issue(11)：1387-1393,7.DOI:10.3969/j.issn.1673-5765.2025.11.007
脑心联合超声造影诊断卵圆孔未闭的应用
Application of Cerebrocardiac Contrast-Enhanced Ultrasound in the Diagnosis of Patent Foramen Ovale
摘要
Abstract
This article systematically reviews the application status,technical characteristics,existing challenges,and future prospects of cerebrocardiac contrast-enhanced ultrasound in the precision diagnosis of patent foramen ovale(PFO).Compared with single-modality contrast-enhanced ultrasound,cerebrocardiac contrast-enhanced ultrasound integrates the advantages of contrast-enhanced transcranial Doppler,contrast-enhanced transthoracic echocardiography,and contrast-enhanced transesophageal echocardiography,enabling"structural-functional"dual-dimensional assessment,significantly improving the detection rate and diagnostic accuracy of PFO.Among them,the synchronous cerebrocardiac contrast-enhanced ultrasound allows single-contrast injection with dual-modality assessment,thereby optimizing the diagnosis and treatment process and reducing costs.The asynchronous cerebrocardiac contrast-enhanced ultrasound can provide key anatomical and functional evidence for the selection of indications for PFO closure,determination of device specifications,and prediction of stroke risk.This article also discusses the challenges faced by cerebrocardiac contrast-enhanced ultrasound,such as strong operator dependence and non-unified standards,and prospects future development directions including artificial intelligence empowerment,equipment innovation,and consensus formulation,aiming to provide theoretical basis and clinical practical guidance for promoting precision diagnosis and treatment of PFO.关键词
卵圆孔未闭/右向左分流/对比增强经颅多普勒超声/对比增强经胸超声心动图/多模态超声Key words
Patent foramen ovale/Right to left shunt/Contrast-enhanced transcranial Doppler/Contrast-enhanced transthoracic echocardiography/Multimodal ultrasound分类
医药卫生引用本文复制引用
黄旭明,甘清月,曹黎明..脑心联合超声造影诊断卵圆孔未闭的应用[J].中国卒中杂志,2025,20(11):1387-1393,7.基金项目
深圳市第二人民医院高水平医院建设专项(4004013)2025年度深圳市神经系统疾病临床医学研究中心开放课题(SCRCND202503)深圳市医防融合(神经系统疾病)项目(深卫健体改[2019]25号) （4004013）
