中国卒中杂志2025，Vol.20Issue(11)：1394-1401,8.DOI:10.3969/j.issn.1673-5765.2025.11.008
卵圆孔未闭相关卒中的精准诊断与风险分层策略
Precision Diagnosis and Risk Stratification Strategies for Patent Foramen Ovale-Related Stroke
摘要
Abstract
Patent foramen ovale(PFO)is one of the most common congenital cardiac anomalies in adults.As an intervenable cause of cryptogenic stroke,ischemic stroke induced by PFO is characterized by a high recurrence rate,severe neurological impairment,and potential risk of multi-organ embolism.Precise identification of PFO-related stroke patients and treatment with transcatheter PFO closure can significantly improve neurological prognosis.PFO can cause stroke through mechanisms such as paradoxical embolism and in-situ thrombosis.Therefore,the management of PFO-related stroke requires integrating information including PFO anatomical and functional characteristics as well as clinical manifestations of stroke.Risk assessment should be performed using the risk of paradoxical embolism score and the PFO-associated stroke causal likelihood classification system,followed by the formulation of reasonable and individualized treatment plans(such as drug treatment,interventional therapy,and surgical treatment)to reduce stroke recurrence risk and enhance patient outcomes.This article reviews the risk assessment,imaging characteristics,and diagnostic strategies for PFO-related stroke,aiming to provide evidence for precise identification and intervention of PFO-related stroke and reducing stroke recurrence.关键词
卵圆孔未闭/隐源性卒中/诊断流程/风险分层/多模态影像Key words
Patent foramen ovale/Cryptogenic stroke/Diagnostic process/Risk stratification/Multimodal imaging分类
医药卫生引用本文复制引用
刘君英,苏颖,江红亮,曹黎明..卵圆孔未闭相关卒中的精准诊断与风险分层策略[J].中国卒中杂志,2025,20(11):1394-1401,8.基金项目
2025年度深圳市神经系统疾病临床医学研究中心开放课题(SCRCND202503)深圳市卫生健康菁英人才培养计划(2024XKG021)深圳市医防融合(神经系统疾病)项目(深卫健体改[2019]25号) （SCRCND202503）
