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GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定

邓利军 李金凤 郭曦雅 胡欣怡 苏志恒 李丹凤

中成药2025,Vol.47Issue(11):3540-3548,9.
中成药2025,Vol.47Issue(11):3540-3548,9.DOI:10.3969/j.issn.1001-1528.2025.11.002

GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定

Analysis of volatile components in Yinhu Ganmao Powder by GC-MS/MS and content determination of nineteen constituents

邓利军 1李金凤 2郭曦雅 2胡欣怡 2苏志恒 2李丹凤3

作者信息

  • 1. 广西医科大学药学院,广西南宁 530021||广西壮族自治区妇幼保健院,广西南宁 530021
  • 2. 广西医科大学药学院,广西南宁 530021
  • 3. 广西壮族自治区药品检验研究院,广西南宁 530021
  • 折叠

摘要

Abstract

AIM To establish a GC-MS/MS method for the analysis of volatile components in Yinhu Ganmao Powder,and to determine the contents of α-pinene,camphene,sabinene,β-pinene,α-terpinene,(+)-limonene,p-cymene,1,8-cineole,linalool,L-menthol,terpinen-4-ol,DL-menthol,α-terpineol,tridecane,pulegone,caryophyllene,humulene,n-hexadecane and patchouli alcohol.METHODS The analysis was performed on a DB-624 UI capillary column(30 m×0.25 mm×1.40 μm ),and electron ionization source was adopted with multiple reaction monitoring mode.RESULTS Fifty volatile components and twenty-five liposoluble components were identified in volatile oils and medicinal material powder,respectively.Nineteen constituents showed good linear relationships within their own ranges(r ≥ 0.999 0),whose average recoveries were 84.43%-113.31%with the RSDs of less than 9.15%.CONCLUSION This stable,accurate and reproducible method can provide a reference for the quality evaluation of Yinhu Ganmao Powder.

关键词

银胡感冒散/挥发性成分/定性分析/含量测定/GC-MS/MS

Key words

Yinhu Ganmao Powder/volatile components/qualitative analysis/content determination/GC-MS/MS

分类

医药卫生

引用本文复制引用

邓利军,李金凤,郭曦雅,胡欣怡,苏志恒,李丹凤..GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定[J].中成药,2025,47(11):3540-3548,9.

基金项目

广西壮族自治区药品监督管理局药品安全科研项目(桂药监科直属[2024]011号) (桂药监科直属[2024]011号)

中成药

OA北大核心

1001-1528

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