中成药2025,Vol.47Issue(11):3540-3548,9.DOI:10.3969/j.issn.1001-1528.2025.11.002
GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定
Analysis of volatile components in Yinhu Ganmao Powder by GC-MS/MS and content determination of nineteen constituents
摘要
Abstract
AIM To establish a GC-MS/MS method for the analysis of volatile components in Yinhu Ganmao Powder,and to determine the contents of α-pinene,camphene,sabinene,β-pinene,α-terpinene,(+)-limonene,p-cymene,1,8-cineole,linalool,L-menthol,terpinen-4-ol,DL-menthol,α-terpineol,tridecane,pulegone,caryophyllene,humulene,n-hexadecane and patchouli alcohol.METHODS The analysis was performed on a DB-624 UI capillary column(30 m×0.25 mm×1.40 μm ),and electron ionization source was adopted with multiple reaction monitoring mode.RESULTS Fifty volatile components and twenty-five liposoluble components were identified in volatile oils and medicinal material powder,respectively.Nineteen constituents showed good linear relationships within their own ranges(r ≥ 0.999 0),whose average recoveries were 84.43%-113.31%with the RSDs of less than 9.15%.CONCLUSION This stable,accurate and reproducible method can provide a reference for the quality evaluation of Yinhu Ganmao Powder.关键词
银胡感冒散/挥发性成分/定性分析/含量测定/GC-MS/MSKey words
Yinhu Ganmao Powder/volatile components/qualitative analysis/content determination/GC-MS/MS分类
医药卫生引用本文复制引用
邓利军,李金凤,郭曦雅,胡欣怡,苏志恒,李丹凤..GC-MS/MS法分析银胡感冒散挥发性成分及19种成分含量测定[J].中成药,2025,47(11):3540-3548,9.基金项目
广西壮族自治区药品监督管理局药品安全科研项目(桂药监科直属[2024]011号) (桂药监科直属[2024]011号)