中成药2025,Vol.47Issue(11):3571-3580,10.DOI:10.3969/j.issn.1001-1528.2025.11.006
Hofmeister系列离子对温经汤挥发油β-环糊精包合物中3种成分包封率的影响
Effects of Hofmeister series ions on encapsulation efficiencies of three components in inclusion complex of volatile oils from Wenjing Decoction
摘要
Abstract
AIM To explore the effects of Hofmeister series ions on encapsulation efficiencies of cinnamaldehyde,paeonol,and ligustilide in inclusion complex of volatile oils from Wenjing Decoction.METHODS The volatile oils were extracted,after which the β-cyclodextrin inclusion complex was prepared,the thermal stability was evaluated,and encapsulation efficiencies and inclusion complex constants of various volatile components in Na2SO4,NaH2PO4,NaCl,NaI,NaSCN solutions were determined.RESULTS The β-cyclodextrin inclusion complex demonstrated good thermal stability within 10 d.After the addtion of Hofmeister series ions,various volatile components displayed increased encapsulation efficiencies and inclusion complex constants,and concentration-dependent manner was observable in the latter.CONCLUSION Hofmeister series ions can affect the binding affinities of volatile components and β-cyclodextrin in volatile oils from Wenjing Decoction,thus regulate their encapsulation efficiencies.关键词
温经汤/挥发油/β-环糊精包合物/Hofmeister系列离子/桂皮醛/丹皮酚/藁本内酯/包封率Key words
Wenjing Decoction/volatile oils/β-cyclodextrin inclusion complex/Hofmeister series ions/cinnamaldehyde/paeonol/ligustilide/encapsulation efficiencies分类
医药卫生引用本文复制引用
沈雯,李卓远,陶琳,谢薇,施润,崔雨晗,李文,李俊松..Hofmeister系列离子对温经汤挥发油β-环糊精包合物中3种成分包封率的影响[J].中成药,2025,47(11):3571-3580,10.基金项目
江苏省自然科学基金项目(BK20190800) (BK20190800)
南京中医药大学自然科学基金项目(XPT82104688) (XPT82104688)