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CRISPR-Cas9系统在反刍动物生产中的应用研究进展

张羽鹏 张宗瑞 张宁 周琛帛 吴苏君 张元庆

中国畜禽种业2025,Vol.21Issue(11):39-50,12.
中国畜禽种业2025,Vol.21Issue(11):39-50,12.

CRISPR-Cas9系统在反刍动物生产中的应用研究进展

Research Progress on Application of CRISPR-cas9 System in Ruminant Production

张羽鹏 1张宗瑞 1张宁 1周琛帛 1吴苏君 1张元庆1

作者信息

  • 1. 山西农业大学动物科学学院,山西太谷 030032
  • 折叠

摘要

Abstract

CRISPR-Cas9 gene editing technology has become a core tool for ruminant genetic improvement which is characterized by its precision,efficiency and low-cost advantages.This paper mainly reviews the research progress of CRISPR-Cas9 technology in the field of ruminant genetic improvement,focusing on the current status of its application in the regulation of growth traits,opti-misation of lactation performance,enhancement of reproduction ability and strengthening of disease resistance mechanisms in cattle and sheep,as well as the technological bottlenecks and ethical controversies faced in the production practice,and looks forward to the prospect of its future application in the field of agriculture from the perspective of molecular breeding,we aimed to Provide the-oretical basis and practical reference for the iterative development of related technologies.

关键词

基因编辑/CRISPR-Cas9///肉品质/泌乳/繁殖/抗病

Key words

Gene editing/CRISPR-Cas9 system/Cattle/Sheep/Meat quality/Lacation/Reproduction/Diease resistance

分类

农业科技

引用本文复制引用

张羽鹏,张宗瑞,张宁,周琛帛,吴苏君,张元庆..CRISPR-Cas9系统在反刍动物生产中的应用研究进展[J].中国畜禽种业,2025,21(11):39-50,12.

基金项目

山西省基础研究计划自然科学研究面上项目(20210302123424) (20210302123424)

山西省农业关键核心技术攻关项目(NYGG22) (NYGG22)

山西省基础研究计划自然科学研究青年项目(20210302124640) (20210302124640)

山西省科技重大专项计划"揭榜挂帅"项目(202201140601026). (202201140601026)

中国畜禽种业

1673-4556

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