中医肿瘤学杂志2025，Vol.7Issue(6)：1-11,11.DOI:10.19811/j.cnki.ISSN2096-6628.2025.11.001
中西医结合分期防治结直肠癌研究述评
A Review of Staged Prevention and Treatment of Colorectal Cancer with Integrated Traditional Chinese and Western Medicine
摘要
Abstract
Colorectal cancer,ranking as the second most common malignant tumor in incidence and the fourth in mortality in China,poses a serious threat to public health.Although modern medical treatments such as surgery,radiotherapy,chemotherapy,and targeted therapy have demonstrated efficacy,they still face challenges including difficulties in blocking the progression of precancerous lesions,significant toxic side effects from radiotherapy and chemotherapy,high rates of postoperative recurrence and metastasis,and limited effectiveness of palliative care for advanced stages.Traditional Chinese medicine has shown prominent effects in inhibiting adenoma recurrence and carcinogenesis,reducing toxic side effects in combination with radiotherapy and chemotherapy,preventing tumor recurrence and metastasis,and improving the quality of life and prolonging survival for advanced patients.Therefore,establishing an integrated traditional Chinese and Western medicine model for the prevention and treatment of colorectal cancer,leveraging the strengths of both approaches,is an inevitable trend in clinical development.This article systematically reviews the pathogenesis,treatment principles and methods,mechanism research,clinical studies,and guidelines/consensus from the perspectives of both traditional Chinese and Western medicine across four key stages of colorectal cancer development(precancerous lesion stage,toxicity reduction during combined therapy,postoperative recurrence prevention,and living with tumor).The aim is to elucidate the synergistic and complementary value of traditional Chinese medicine in the treatment of colorectal cancer at each stage,providing theoretical support and practical guidance for the staged prevention and treatment of colorectal cancer with integrated traditional Chinese and Western medicine.关键词
结直肠癌/中西医结合/分期防治/病因病机/机制研究/临床研究/指南共识Key words
colorectal cancer/integrated traditional Chinese and Western medicine/staged prevention and treatment/etiology and pathogenesis/mechanism research/clinical research/guidelines and consensus分类
医药卫生引用本文复制引用
阚书航,耿雪尘,王俊壹,李柳,程海波..中西医结合分期防治结直肠癌研究述评[J].中医肿瘤学杂志,2025,7(6):1-11,11.基金项目
国家重点研发计划"中医药现代化"重点专项(编号:2022YFC3500200,2022YFC3500201) （编号:2022YFC3500200,2022YFC3500201）
国家中医药管理局高水平中医药重点学科建设项目(编号:国中医药人教函[2023]85号) （编号:国中医药人教函[2023]85号）
国家中医药管理局中医药创新团队及人才支持计划项目(编号:ZYYCXTD-C-202208) （编号:ZYYCXTD-C-202208）
江苏高校优势学科建设工程资助项目-中医学、中西医结合(编号:PAPD) （编号:PAPD）
江苏高校"青蓝工程"资助项目(编号:苏教师函[2023]27号). （编号:苏教师函[2023]27号）
