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scITDG:a tool for identifying time-dependent genes in single-cell transcriptome sequencing data

Yandong Zheng Chengyu Liu Weiqi Zhang Jing Qu Shuai Ma Guang-Hui Liu

Marine Life Science & Technology2025，Vol.7Issue(4)：P.792-807,16.

Marine Life Science & Technology2025，Vol.7Issue(4)：P.792-807,16.DOI:10.1007/s42995-025-00311-y

scITDG:a tool for identifying time-dependent genes in single-cell transcriptome sequencing data

Yandong Zheng ¹Chengyu Liu ¹Weiqi Zhang ²Jing Qu ³Shuai Ma ³Guang-Hui Liu⁴

作者信息

1. State Key Laboratory of Organ Regeneration and Reconstruction,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China Beijing Institute for Stem Cell and Regenerative Medicine,Beijing 100101,China University of Chinese Academy of Sciences,Beijing 100049,China
2. CAS Key Laboratory of Genomic and Precision Medicine,Beijing Institute of Genomics,Chinese Academy of Sciences and China National Center for Bioinformation,Beijing 100101,China University of Chinese Academy of Sciences,Beijing 100049,China Aging Biomarker Consortium,Beijing,China
3. State Key Laboratory of Organ Regeneration and Reconstruction,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China Beijing Institute for Stem Cell and Regenerative Medicine,Beijing 100101,China University of Chinese Academy of Sciences,Beijing 100049,China Aging Biomarker Consortium,Beijing,China
4. State Key Laboratory of Organ Regeneration and Reconstruction,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China Beijing Institute for Stem Cell and Regenerative Medicine,Beijing 100101,China University of Chinese Academy of Sciences,Beijing 100049,China Advanced Innovation Center for Human Brain Protection,National Clinical Research Center for Geriatric Disorders,Xuanwu Hospital Capital Medical University,Beijing 100053,China Aging Translational Medicine Center,International Center for Aging and Cancer,Beijing Municipal Geriatric Medical Research Center,Xuan Wu Hospital,Capital Medical University,Beijing 100053,China Aging Biomarker Consortium,Beijing,China
折叠

摘要

关键词

Aging/Regeneration/scITDG R package/Single-cell sequencing/Time-dependent genes

分类

生物科学

引用本文复制引用

Yandong Zheng,Chengyu Liu,Weiqi Zhang,Jing Qu,Shuai Ma,Guang-Hui Liu..scITDG:a tool for identifying time-dependent genes in single-cell transcriptome sequencing data[J].Marine Life Science & Technology,2025,7(4):P.792-807,16.

基金项目

supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0200000) （XDC0200000）

the National Natural Science Foundation of China(82322025,82488301,82125011,82271600,82361148131) （82322025,82488301,82125011,82271600,82361148131）

the National Key Research and Development Pro-gram of China(2022YFA1103700,2020YFA0804000) （2022YFA1103700,2020YFA0804000）

the Stra-tegic Priority Research Program of the Chinese Academy of Sci-ences(XDA0460403) （XDA0460403）

the National Natural Science Foundation of China(92168201,82330044,32341001,32121001,82192863,82361148130,8231101626) （92168201,82330044,32341001,32121001,82192863,82361148130,8231101626）

Non-Communicable Chronic Diseases-National Science and Technology Major Project(2024ZD0530400) （2024ZD0530400）

Youth Innovation Promotion Association of CAS(2022083) （2022083）

Young Elite Scientists Sponsorship Program by CAST(2021QNRC001) （2021QNRC001）

International Partnership Program of Chinese Academy of Sciences(073GJHZ2023019FN) （073GJHZ2023019FN）

he Program of the Beijing Natural Science Foundation(JQ24044,Z240018,F251011,Z230011) （JQ24044,Z240018,F251011,Z230011）

Shenzhen Medi-cal Research Fund(C2406001) （C2406001）

CAS Project for Young Scientists in Basic Research(YSBR-076,YSBR-012) （YSBR-076,YSBR-012）

the Informatization Plan of Chinese Academy of Sciences(CAS-WX2022SDC-XK14) （CAS-WX2022SDC-XK14）

New Cor-nerstone Science Foundation through the XPLORER PRIZE(2021-1045) （2021-1045）

Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes(JYY2023-13) （JYY2023-13）

CAS Youth Interdisciplinary Team,Key Laboratory of Alzheimer''s Disease of Zhejiang Province(ZJAD-2024001) （ZJAD-2024001）

Initiative Scientific Research Program,Institute of Zoology,CAS(2023IOZ0102,2023IOZ0202,2024IOZ0103) （2023IOZ0102,2023IOZ0202,2024IOZ0103）

Beijing Anzhen Hospital High Level Research Funding(2024AZB3002). （2024AZB3002）

Marine Life Science & Technology

ISSN：2096-6490

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