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Mechanistic Insights into the Role of Melatonin in Cancer Cell Chemoresistance

Russel J.Reiter Ramaswamy Sharma Walter Manucha Walter Balduini Doris Loh Demetrios A.Spandidos Alejandro Romero Vasiliki E.Georgakopoulou Wei Zhu

BIOCELL2025,Vol.49Issue(11):P.2033-2067,35.
BIOCELL2025,Vol.49Issue(11):P.2033-2067,35.DOI:10.32604/biocell.2025.067661

Mechanistic Insights into the Role of Melatonin in Cancer Cell Chemoresistance

Russel J.Reiter 1Ramaswamy Sharma 2Walter Manucha 3Walter Balduini 4Doris Loh 5Demetrios A.Spandidos 6Alejandro Romero 7Vasiliki E.Georgakopoulou 8Wei Zhu9

作者信息

  • 1. Department of Cell Systems and Anatomy,UT Health San Antonio,Long School of Medicine,San Antonio,TX 78229,USA
  • 2. Applied Biomedical Sciences,University of the Incarnate Word,School of Osteopathic Medicine,San Antonio,TX 78209,USA
  • 3. Instituto de Medicina y Biologia Experimental de Cuyo(IMBECU),Consejo Nacional de Investigaciones Cientificas y Tecnologicas(CONICET),Mendoza,5500,Argentina
  • 4. Department of Biomolecular Sciences,University of Urbino Carlo Bo,Urbino,61029,Italy
  • 5. Independent Researcher,Marble Falls,TX 78654,USA
  • 6. Laboratory of Clinical Virology,School of Medicine,University of Crete,Heraklion,71003,Greece
  • 7. Department of Pharmacology and Toxicology,Faculty of Veterinary Medicine,Complutense University of Madrid,Madrid,28040,Spain
  • 8. Department of Pathophysiology,Laiko General Hospital,National and Kapodistrian University of Athens,Athens,11527,Greece
  • 9. SCI Research Institute,Jericho,New York,NY 11753,USA
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摘要

关键词

Free radicals/oxidative stress/mitochondrial matrix/antioxidant/PI3K/AKT/mTOR signaling/Warburg metabolism/biomolecular condensates/thymidylate synthase/microRNAs/pyruvate metabolism

分类

医药卫生

引用本文复制引用

Russel J.Reiter,Ramaswamy Sharma,Walter Manucha,Walter Balduini,Doris Loh,Demetrios A.Spandidos,Alejandro Romero,Vasiliki E.Georgakopoulou,Wei Zhu..Mechanistic Insights into the Role of Melatonin in Cancer Cell Chemoresistance[J].BIOCELL,2025,49(11):P.2033-2067,35.

BIOCELL

0327-9545

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