首页|期刊导航|Virologica Sinica|Ubiquitously expressed transcript isoform 2(UXT-V2)restricts HSV-2 replication by targeting glycoprotein B for degradation through ubiquitin-proteasome pathway

Ubiquitously expressed transcript isoform 2(UXT-V2)restricts HSV-2 replication by targeting glycoprotein B for degradation through ubiquitin-proteasome pathway

Chuntian Li Yuncheng Li Ranqing Cheng Miaomiao Li Mudan Zhang Zhiyuan Zhu Ping Yang Qinxue Hu Yalan Liu

Virologica Sinica2025，Vol.40Issue(5)：P.778-792,15.

Virologica Sinica2025，Vol.40Issue(5)：P.778-792,15.DOI:10.1016/j.virs.2025.08.004

Ubiquitously expressed transcript isoform 2(UXT-V2)restricts HSV-2 replication by targeting glycoprotein B for degradation through ubiquitin-proteasome pathway

Chuntian Li ¹Yuncheng Li ²Ranqing Cheng ²Miaomiao Li ²Mudan Zhang ³Zhiyuan Zhu ²Ping Yang ³Qinxue Hu ²Yalan Liu⁴

作者信息

1. Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of Henan University,School of Medicine,Henan University,Kaifeng,475004,China
2. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430071,China Savaid Medical School,University of Chinese Academy of Sciences,Beijing,100049,China
3. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430071,China
4. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430071,China Savaid Medical School,University of Chinese Academy of Sciences,Beijing,100049,China Hubei Jiangxia Laboratory,Wuhan,430200,China
折叠

摘要

关键词

Herpes simplex virus 2(HSV-2)/UXT-V2/Glycoprotein B(gB)/Ubiquitination

分类

医药卫生

引用本文复制引用

Chuntian Li,Yuncheng Li,Ranqing Cheng,Miaomiao Li,Mudan Zhang,Zhiyuan Zhu,Ping Yang,Qinxue Hu,Yalan Liu..Ubiquitously expressed transcript isoform 2(UXT-V2)restricts HSV-2 replication by targeting glycoprotein B for degradation through ubiquitin-proteasome pathway[J].Virologica Sinica,2025,40(5):P.778-792,15.

基金项目

supported by the National Natural Science Foundation of China(82472272 and 82171736) （82472272 and 82171736）

the National Key Research and Development Program of China(2022YFC2304301 and 2023YFC2306600). （2022YFC2304301 and 2023YFC2306600）

Virologica Sinica

ISSN：1674-0769

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