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Multi-Omics Insights into the Impact of MDH2 on Breast Cancer Progression: A Promising Druggable Target

Botao Pan Zirun Luo Xiujuan Yang Qingqing Liu Zhimin Yang Chenglai Xia

Oncology Research2025，Vol.33Issue(11)：P.3557-3582,26.

Oncology Research2025，Vol.33Issue(11)：P.3557-3582,26.DOI:10.32604/or.2025.068119

Multi-Omics Insights into the Impact of MDH2 on Breast Cancer Progression: A Promising Druggable Target

Botao Pan ¹Zirun Luo ²Xiujuan Yang ¹Qingqing Liu ³Zhimin Yang ⁴Chenglai Xia⁵

作者信息

1. Scientific Research Center,The Affiliated Foshan Women and Children Hospital,Guangdong Medical University,Foshan,528000,China
2. Department of Breast,Thyroid and Head-Neck Surgery,Third Xiangya Hospital of Central South University,Changsha,410000,China
3. School of Pharmaceutical Sciences,Southern Medical University,Guangzhou,515150,China
4. Jiangsu Natural Active Pharmaceutical Ingredient Design and Separation Technology Engineering Research Center,School of Pharmaceutical Engineering,Jiangsu Food&Pharmaceutical Science College,Huai’an,223003,China
5. Scientific Research Center,The Affiliated Foshan Women and Children Hospital,Guangdong Medical University,Foshan,528000,China School of Pharmaceutical Sciences,Southern Medical University,Guangzhou,515150,China
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摘要

关键词

Breast cancer/cancer metabolism/malate dehydrogenase 2(MDH2)/druggable target/immunomodulatory metabolites

分类

医药卫生

引用本文复制引用

Botao Pan,Zirun Luo,Xiujuan Yang,Qingqing Liu,Zhimin Yang,Chenglai Xia..Multi-Omics Insights into the Impact of MDH2 on Breast Cancer Progression: A Promising Druggable Target[J].Oncology Research,2025,33(11):P.3557-3582,26.

基金项目

supported by grants from the GuangDong Basic and Applied Basic Research Foundation(2023B1515130009) （2023B1515130009）

the Science and Technology Bureau of Foshan(No.FS0AA-KJ819-4901-0082). （No.FS0AA-KJ819-4901-0082）

Oncology Research

ISSN：0965-0407

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