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Isoliquiritigenin Inhibits Triple-Negative Breast Cancer Progression via Targeting the IRF5/SLC7A5/IDO1-Mediated Tryptophan Metabolism Pathway

Sihai Duan Xiaoyan Li Cailu Song Song Wu Yunyun Tang Qing Bao Na Li Hailin Tang

Oncology Research2025，Vol.33Issue(11)：P.3543-3556,14.

Oncology Research2025，Vol.33Issue(11)：P.3543-3556,14.DOI:10.32604/or.2025.068292

Isoliquiritigenin Inhibits Triple-Negative Breast Cancer Progression via Targeting the IRF5/SLC7A5/IDO1-Mediated Tryptophan Metabolism Pathway

Sihai Duan ¹Xiaoyan Li ²Cailu Song ²Song Wu ²Yunyun Tang ³Qing Bao ³Na Li ²Hailin Tang²

作者信息

1. Department of Breast and Thyroid Surgery,The Central Hospital of Yongzhou,Yongzhou,425007,China Department of Breast and Thyroid Surgery,Yongzhou Hospital Affiliated to University of South China,Yongzhou,425007,China
2. State Key Laboratory of Oncology in South China,Guangdong Provincial Clinical Research Center for Cancer,Sun Yat-sen University Cancer Center,Guangzhou,510060,China
3. State Key Laboratory of Oncology in South China,Guangdong Provincial Clinical Research Center for Cancer,Sun Yat-sen University Cancer Center,Guangzhou,510060,China Department of Basic Medicine,School of Health and Wellness Sciences,Guangzhou Kangda Vocational Technical College,Guangzhou,510555,China
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摘要

关键词

Interferon regulatory factor 5(IRF5)/triple-negative breast cancer/tryptophan metabolism/isoliquiritigenin/solute carrier family 7 member 5(SLC7A5)/indoleamine 2,3-dioxygenase 1(IDO1)

分类

医药卫生

引用本文复制引用

Sihai Duan,Xiaoyan Li,Cailu Song,Song Wu,Yunyun Tang,Qing Bao,Na Li,Hailin Tang..Isoliquiritigenin Inhibits Triple-Negative Breast Cancer Progression via Targeting the IRF5/SLC7A5/IDO1-Mediated Tryptophan Metabolism Pathway[J].Oncology Research,2025,33(11):P.3543-3556,14.

基金项目

supported by the Science and Technology Program of Guangzhou(No.202103000020). （No.202103000020）

Oncology Research

ISSN：0965-0407

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