Journal of Biomedical Research2025，Vol.39Issue(6)：P.574-586,I0006-I0010,18.DOI:10.7555/JBR.38.20240389
Osbpl2 deficiency inhibits Rho/ROCK2/p-ERM signaling and impairs actin cytoskeletal regulation in auditory cells
Cheng Zhang 1Qian Yang 1Yajie Lu 2Qinjun Wei 2Rong Zhou 3Guangqian Xing 4Xin Cao 2Zhibin Chen 4Jun Yao5
作者信息
- 1. Department of Medical Genetics,School of Basic Medical Sciences,Nanjing Medical University,Nanjing,Jiangsu 211166,China
- 2. Department of Medical Genetics,School of Basic Medical Sciences,Nanjing Medical University,Nanjing,Jiangsu 211166,China Jiangsu Key Laboratory of Xenotransplantation,Nanjing Medical University,Nanjing,Jiangsu 211166,China
- 3. Department of Physiology,School of Basic Medical Sciences,Nanjing Medical University,Nanjing,Jiangsu 211166,China
- 4. Department of Otolaryngology,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
- 5. Department of Medical Genetics,School of Basic Medical Sciences,Nanjing Medical University,Nanjing,Jiangsu 211166,China Jiangsu Key Laboratory of Xenotransplantation,Nanjing Medical University,Nanjing,Jiangsu 211166,China Department of Otolaryngology-Head and Neck Surgery,the Affiliated Taizhou People''s Hospital of Nanjing Medical University,Taizhou School of Clinical Medicine,Nanjing Medical University,Taizhou,Jiangsu 225300,China
- 折叠
摘要
关键词
OSBPL2/hearing loss/actin cytoskeleton/Rho/ROCK signaling/p-ERM分类
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Cheng Zhang,Qian Yang,Yajie Lu,Qinjun Wei,Rong Zhou,Guangqian Xing,Xin Cao,Zhibin Chen,Jun Yao..Osbpl2 deficiency inhibits Rho/ROCK2/p-ERM signaling and impairs actin cytoskeletal regulation in auditory cells[J].Journal of Biomedical Research,2025,39(6):P.574-586,I0006-I0010,18.基金项目
financially supported by the National Natural Science Foundation of China(Grant Nos.82071052 to J.Y.and 81771000 to X.C.)。 （Grant Nos.82071052 to J.Y.and 81771000 to X.C.）
