实用临床医药杂志2025，Vol.29Issue(22)：14-17,23,5.DOI:10.7619/jcmp.20254994
全腔镜食管癌切除术后颈部吻合口漏发生的危险因素
Risk factors for cervical anastomotic leakage after totally minimally invasive esophagectomy for esophageal cancer
摘要
Abstract
Objective To analyze risk factors for cervical anastomotic leakage after totally mini-mally invasive esophagectomy for esophageal cancer.Methods Clinical data of 539 patients with e-sophageal cancer who underwent totally minimally invasive esophagectomy at The Fourth Hospital of Hebei Medical University from September 2013 to November 2021 were retrospectively analyzed.Mul-tivariable Logistic regression analysis was employed to screen for risk factors associated with postopera-tive cervical anastomotic leakage.Results Among 539 patients,cervical anastomotic leakage oc-curred in 99 cases,with an incidence rate of 18.37％.Univariable analysis revealed that American Society of Anesthesiologists(ASA)grade,liver cirrhosis,anastomotic location,and anastomotic technique were significantly associated with cervical anastomotic leakage(P＜0.05).Multivariable Logistic regression analysis demonstrated that liver cirrhosis(OR=2.006,95％CI:0.989 to 3.890,P=0.044)and manual anastomosis(OR=1.993,95％CI:1.140 to 2.842,P=0.046)were independent risk factors for cervical anastomotic leakage after totally minimally invasive esoph-agectomy.Conclusion Attention to risk factors for cervical anastomotic leakage,optimization of perioperative management,and accumulation of surgical experience are crucial for preventing cervical anastomotic leakage following minimally invasive esophagectomy.关键词
食管癌/颈部吻合口漏/全腔镜手术/危险因素/肝硬化/吻合技术/回顾性研究/围术期管理Key words
esophageal cancer/cervical anastomotic leakage/totally minimally invasive surgery/risk factors/liver cirrhosis/anastomotic technique/retrospective study/perioperative management分类
医药卫生引用本文复制引用
GUO Jinyang,HUANG Chao,XU Yanzhao..全腔镜食管癌切除术后颈部吻合口漏发生的危险因素[J].实用临床医药杂志,2025,29(22):14-17,23,5.基金项目
河北省医学科学研究课题计划项目(20250882) （20250882）
河北省食管癌精准诊断与综合治疗重点实验室(SZX202304) （SZX202304）
