临床肝胆病杂志2025，Vol.41Issue(11)：2207-2212,6.DOI:10.12449/JCH251102
肝病数字活检的关键技术与应用前景
Digital biopsy for liver diseases:A review of technological advances and application prospects
摘要
Abstract
Digital biopsy for liver diseases is characterized by the deep integration of artificial intelligence(AI)technologies and large-scale liver disease data,through which intelligent analytics are applied to support clinical decision-making and full-cycle management.This article reviews the AI technical framework based on standardized data governance and centered on multimodal large medical models,covering the application of natural language processing,knowledge map,generative AI,and large language models in the establishment of databases for specialty diseases,diagnosis,prognosis prediction,treatment,and automated medical documentation.This article also discusses the application prospects of this framework in medical education,scientific research,and healthcare management.Although this technique shows broad application potential,it still faces challenges in areas such as multi-center data integration,model interpretability,ethics,and data security.In the future,a smart ecosystem with closed-loop optimization and human-AI collaboration should be established to promote the comprehensive implementation of digital biopsy in the whole process of medicine,education,research,and management,thereby providing help for the precise prevention and control and holistic health management of liver diseases.关键词
肝病数字活检平台/人工智能/数据库Key words
Liver Disease Digital Biopsy Platform/Artificial Intelligence/Databases引用本文复制引用
ZHOU Yang,CHEN Zhenwei,SHI Hanying,LIN Kongying,WANG Yingchao,ZENG Yongyi..肝病数字活检的关键技术与应用前景[J].临床肝胆病杂志,2025,41(11):2207-2212,6.基金项目
国家自然科学基金面上项目(62275050) （62275050）
国家重点研发计划(2022YFC2407304) （2022YFC2407304）
福建省自然科学基金计划项目(2025J011318) （2025J011318）
福州市科技计划项目(2024-G-015) National Natural Science Foundation of China(62275050) （2024-G-015）
National Key Research and Development Program of China(2022YFC2407304) （2022YFC2407304）
Natural Science Foundation of Fujian Province(2025J011318) （2025J011318）
Fuzhou Science and Technology Program(2024-G-015) （2024-G-015）
