临床肝胆病杂志2025，Vol.41Issue(11)：2227-2234,8.DOI:10.12449/JCH251105
人工智能相关肝病临床试验的方法学考量
Application of artificial intelligence in clinical trials of liver diseases:A methodological perspective
SHI Lichen 1FENG Ruishi 1JIA Jidong 1YOU Hong 1KONG Yuanyuan1
作者信息
- 1. @@@a.Clinical Epidemiology and EBM Unit of Beijing Clinical Research Institute,b.Liver Research Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China
- 折叠
摘要
Abstract
In recent years,the exploration and development of artificial intelligence(AI)technology in clinical trials for liver diseases have promoted the continuous innovation of research methods and processes in this field.AI has gradually become an important technical tool for various links of clinical trial including patient selection,risk stratification,endpoint evaluation,and result interpretation.Nevertheless,the standardized integration of AI into clinical trials still faces the methodological challenges such as data quality control,model interpretability,and causal inference.From the perspective of methodology,this article systematically reviews the principal application scenarios of AI as an object under investigation(validation trials)and as a research tool(supportive trials)in clinical trials for liver diseases,as well as the major methodological challenges of AI-related clinical trials along and the corresponding solution strategies,in order to provide methodological guidance for promoting the scientific and standardized implementation of AI technologies.关键词
肝疾病/临床试验/人工智能/方法Key words
Liver Diseases/Clinical Trial/Artificial Intelligence/Methods引用本文复制引用
SHI Lichen,FENG Ruishi,JIA Jidong,YOU Hong,KONG Yuanyuan..人工智能相关肝病临床试验的方法学考量[J].临床肝胆病杂志,2025,41(11):2227-2234,8.
