兽类学报2025，Vol.45Issue(6)：743-752,10.DOI:10.16829/j.slxb.151084
蝙蝠回声定位听觉基础的电生理研究范式及其进展
Electrophysiological recording paradigms and advances in the study of auditory basis of echolocation in bats
摘要
Abstract
As the only mammals capable of powered flight,coupled with their remarkable echolocation ability,bats occu-py a unique niche in the night sky and represent one of the most diverse mammalian lineages.Electrophysiological meth-ods,primarily involving the recording of neural activity,significantly advanced our understanding of the neural mecha-nisms underlying bat echolocation.This review details the advantages and disadvantages of three primary electrophysio-logical recording paradigms:recordings under anesthesia,head-fixed recordings,and recordings during free movement.Recordings under anesthesia are useful for studying the functions of neurons in specific brain regions,but anesthetic drugs may interfere with neural activity.Head-fixed recordings can capture neural activity in awake animals but typical-ly restrict their behavioral range.Recordings during free movement are the recommended electrophysiological para-digm,as they most closely match the animals' natural behaviors.Recently,the application of new technologies such as optogenetics,chemogenetics,and two-photon calcium imaging have opened new avenues for studying the neural mecha-nisms of bat echolocation.Future research may combine multiple electrophysiological methods with these emerging technologies to better reveal the neural basis of bat echolocation.关键词
蝙蝠回声定位/电生理研究范式/麻醉状态/头部固定状态/自由活动状态Key words
Bat echolocation/Recording paradigms/Anesthesia/Head-fixed/Free moving分类
生物科学引用本文复制引用
ZHOU Shiyu,ZHANG Di,YE Huan,LUO Jinhong..蝙蝠回声定位听觉基础的电生理研究范式及其进展[J].兽类学报,2025,45(6):743-752,10.基金项目
国家自然科学基金面上项目(32270535) （32270535）
华中师范大学2024年校级教学研究项目(202453) （202453）
