临床医学工程2025，Vol.32Issue(12)：1329-1333,5.DOI:10.3969/j.issn.1674-4659.2025.12.1329
颈部血管彩色超声联合超声造影评估脑梗死颈动脉斑块性质的价值分析
Analysis on the Value of Color Doppler Ultrasound Combined with Contrast-Enhanced Ultrasound of Cervical Vessels in Evaluating the Nature of Carotid Artery Plaques in Cerebral Infarction
摘要
Abstract
Objective To analyze the value of color Doppler ultrasound combined with contrast-enhanced ultrasound(CEUS)of cervical vessels in evaluating the nature of carotid artery plaques in cerebral infarction.Methods The medical records of 90 cerebral infarction patients admitted to the First Affiliated Hospital of Nanyang Medical College from July 2022 to August 2024 were retrospectively analyzed.All patients underwent cervical vessels color Doppler ultrasound,CEUS and digital subtraction angiography(DSA)examinations.Using DSA test results as the"gold standard"for diagnosing the nature of carotid artery plaques in cerebral infarction,the results of color Doppler ultrasound,CEUS,and their combined examination were statistically analyzed,the evaluation value of different examination methods for the nature of carotid plaque in cerebral infarction was compared,and the consistency with DSA examination results was analyzed,the relevant parameters of CEUS for carotid artery plaques of different natures were also compared.Results Among 90 patients with cerebral infarction,95 carotid artery plaques were diagnosed by DSA examination,including 59 stable plaques and 36 unstable plaques.Color ultrasound of cervical vessels detected 58 stable plaques and 37 unstable plaques,CEUS detected 61 stable plaques and 34 unstable plaques,their combined examination detected 60 stable plaques and 35 unstable plaques.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of the combined examination(color Doppler ultrasound+CEUS)for evaluating unstable carotid artery plaques in cerebral infarction were higher than those of color Doppler ultrasound or CEUS alone(P<0.05).Consistency testing showed that the result of color Doppler ultrasound and CEUS had fair agreement with DSA result(Kappa values=0.488,0.593,P=0.000,0.000),while their combined examination result showed good agreement with DSA result(Kappa value=0.978,P=0.000).The arrival time of the contrast agent,the peak time of the plaque,and the transit time in the CEUS examination of unstable plaques were all shorter than those of stable plaques,and the maximum enhancement intensity was greater than that of stable plaques(P<0.05).Conclusions Color Doppler ultrasound combined with CEUS of cervical vessels has high value in evaluating the nature of carotid artery plaques in cerebral infarction.Their combined examination result show good agreement with DSA results,which helps in clearly evaluating the nature of carotid plaques and provides an important reference for clinicians to accurately assess the patients'condition and formulate personalized treatment plans.关键词
脑梗死/颈动脉斑块/颈部血管/彩色超声/超声造影/评估价值Key words
Cerebral infarction/Carotid artery plaque/Cervical vessel/Color Doppler ultrasound/Contrast-enhanced ultrasound/Evaluation value分类
医药卫生引用本文复制引用
LIU Han,LI Caiyun,LIU Yusen,SONG Yan..颈部血管彩色超声联合超声造影评估脑梗死颈动脉斑块性质的价值分析[J].临床医学工程,2025,32(12):1329-1333,5.基金项目
河南省医学科技攻关计划联合共建项目(项目编号:LHGJ20191467) （项目编号:LHGJ20191467）
