临床医学工程2025，Vol.32Issue(12)：1363-1366,4.DOI:10.3969/j.issn.1674-4659.2025.12.1363
AngioJet机械血栓清除术联合导管接触溶栓在下肢深静脉血栓形成中的应用研究
Study on the Application of AngioJet Mechanical Thrombectomy Combined with Catheter-Directed Thrombolysis in Lower Extremity Deep Vein Throm-bosis
摘要
Abstract
Objective To investigate the effect of AngioJet mechanical thrombectomy combined with catheter-directed thrombolysis(CDT)on patients with lower extremity deep vein thrombosis(DVT).Methods The clinical data of 95 DVT patients admitted to our hospital from January 2021 to December 2024 were retrospectively analyzed.Based on the treatment method,they were divided into two groups:48 patients who underwent CDT alone were assigned to the control group,and 47 patients who underwent AngioJet mechanical thrombectomy combined with CDT were assigned to the observation group.The thrombolytic efficacy,perioperative indicators,affected limb circumference,coagulation function,and adverse reactions were compared between the two groups.Results The total effective rate of thrombolysis in the observation group was higher than that in the control group(P<0.05).The thrombolysis time,hospital stay,and swelling resolution time in the observation group were shorter than those in the control group,the total dosage of urokinase used was less than that in the control group,and the thrombus clearance rate was higher than that in the control group(P<0.05).After treatment,the differences in circumference above and below the knee in the observation group were smaller than those in the control group,and the levels of D-dimer and fibrinogen(FIB)were lower than those in the control group(P<0.05).No severe adverse reactions occurred in either group.Conclusions AngioJet mechanical thrombectomy combined with CDT can significantly improve thrombolytic efficacy,reduce the dosage of thrombolytic drugs,shorten hospital stays,reduce the circumference difference of the affected limb,help improve coagulation function,and demonstrates good effectiveness and safety.关键词
下肢深静脉血栓形成/导管接触溶栓/AngioJet机械血栓清除术Key words
Lower extremity deep vein thrombosis/Catheter-directed thrombolysis/AngioJet mechanical thrombectomy分类
医药卫生引用本文复制引用
YIN Huashan,SU Xiaoxue,JI Aihua,ZHANG Meng,CUI Xuebin..AngioJet机械血栓清除术联合导管接触溶栓在下肢深静脉血栓形成中的应用研究[J].临床医学工程,2025,32(12):1363-1366,4.基金项目
潍坊市卫健委科研项目(项目编号:WFWSJK-2022-099) （项目编号:WFWSJK-2022-099）
