中国实验动物学报2025，Vol.33Issue(11)：1663-1671,9.DOI:10.3969/j.issn.1005-4847.2025.11.010
粪菌移植治疗慢性腹泻的研究进展
Research progress on fecal microbiota transplantation for the treatment of chronic diarrhea
摘要
Abstract
Fecal microbiota transplantation(FMT)is a therapeutic method in which microorganisms are transplanted from healthy donors'feces into the gastrointestinal tract of patients,to directly change their intestinal microbiota,normalize its composition,and achieve therapeutic effects.Chronic diarrhea is closely associated with the gut microbiota and an imbalance in the gut microbiota can lead to the occurrence and progression of chronic diarrhea.FMT is an effective approach for the treatment of chronic diarrhea.This review summarizes the relationship between chronic diarrhea and the gut microbiota and considers research advancements and applications of FMT technology for managing chronic diarrhea.We also address the prevailing challenges and future prospects,to provide a reference for further studies of FMT for the treatment of chronic diarrhea.关键词
粪菌移植/肠道微生物群/慢性腹泻/研究进展Key words
fecal microbiota transplantation/gut microbiota community/chronic diarrhea/research progress分类
生物科学引用本文复制引用
QIAN Ziyao,LI Heling,WANG Hong..粪菌移植治疗慢性腹泻的研究进展[J].中国实验动物学报,2025,33(11):1663-1671,9.基金项目
国家自然科学基金项目(31960121). Funded by the National Natural Science Foundation of China(31960121). （31960121）
