中国实用妇科与产科杂志2025，Vol.41Issue(11)：1073-1079,7.DOI:10.19538/j.fk2025110105
胚胎植入前非整倍体检测技术能否改善复发性流产患者的活产率
Whether PGT-A could improve live birth rate of patients with recurrent spontaneous abortion
摘要
Abstract
Recurrent spontaneous abortion(RSA)refers to two or more consecutive miscarriages that occur before 28 weeks of pregnancy,including biochemical pregnancy miscarriages with the same partner.Considering the increased risk of embryonic aneuploidy,RSA has been listed as one of the common clinical indications for preimplantation genetic testing for aneuploidy(PGT-A).Although PGT-A has been widely implemented worldwide,its specific application population and whether it can improve the live birth rate of RSA patients have been controversial.This article summarizes the contradictions in the live birth rate outcomes of RSA patients after PGT-A treatment based on patient age,RSA type,calculation method of live birth rate,embryo transfer strategy in the control group,PGT detection technology,and cost-effectiveness analysis.In the future,high-quality randomized controlled trials(RCTs)are needed to provide high-quality evidence-based medical evidence for the effectiveness and safety of PGT-A treatment for RSA patients.关键词
复发性流产/胚胎植入前非整倍体检测技术/活产率/流产率/高龄孕妇Key words
recurrent spontaneous abortion/preimplanta-tion genetic testing for aneuploidy/live birth rate/miscar-riage rate/advanced maternal age分类
医药卫生引用本文复制引用
XIE Yu-le,LIU Yang,NI Tian-xiang,YAN Jun-hao..胚胎植入前非整倍体检测技术能否改善复发性流产患者的活产率[J].中国实用妇科与产科杂志,2025,41(11):1073-1079,7.基金项目
国家重点研发计划(2024YFC2706700) National Key Research and Development Program of China(2024YFC2706700) （2024YFC2706700）
