中国中西医结合急救杂志2025，Vol.32Issue(4)：385-391,7.DOI:10.3969/j.issn.1008-9691.2025.04.001
基于"壮火食气"探析支气管扩张症合并铜绿假单胞菌感染的病理内涵及治疗指导意义
To explore the pathological connotation and therapeutic significance of bronchiectasis combined with Pseudomonas aeruginosa infection based on"Strengthening fire eating qi"
摘要
Abstract
Bronchiectasis is one of the most common and refractory lower respiratory tract diseases in clinic practice.Pseudomonas aeruginosa is the most common frequently isolated pathogen in adults with bronchiectasis complicated by infection.The complex relationship among inflammation,immunity,infection and structural damage in the airway of patients has been described as a"vicious circle"model,but the specific mechanism of different pathological links in this model and their intricate interactions are still not fully understood.The theory of"Strengthening fire eating qi"first appeared in Su Wen·Yin Yang Ying Xiang Da Lun,and provides simply explain the"qi"damage to"shape"damage of patients'airway from the perspective of"fire"and"qi"in traditional Chinese medicine,and provide new ideas for explaining the pathological mechanism connotation of bronchiectasis combined with Pseudomonas aeruginosa infection.The exploration of pathological mechanism is the fundamental source of understanding disease progression and discovering new treatment ideas.At present,the clinical treatment of Western medicine for patients with bronchiectasis mainly focuses on anti-infection and symptomatic treatment.Although etiological targeted therapies and targeted drugs are constantly explored and developed,they are still rarely applied in clinical practice.As a treasure of Chinese culture,traditional Chinese medicine has the advantage of taking both specimens into consideration,and its clinical efficacy and pharmacological value are worthy of further study.Based on the classical theory of"Strengthening fire eating qi",this review aims to understand and summarize the modern pathological mechanism of bronchiectasis combined with Pseudomonas aeruginosa infection and highlights current research hotspots in both Chinese and Western medicine treatment,in order to provide clinical thinking.关键词
壮火食气/支气管扩张症/铜绿假单胞菌/病理机制/治疗思路Key words
Strengthening fire eating qi/Bronchiectasis/Pseudomonas aeruginosa/Pathomechanism/Treatment thoughts引用本文复制引用
Wang Xiaoyu,Feng Zhenzhen,Liu Wenrui,Li Jiansheng..基于"壮火食气"探析支气管扩张症合并铜绿假单胞菌感染的病理内涵及治疗指导意义[J].中国中西医结合急救杂志,2025,32(4):385-391,7.基金项目
河南省中医学"双一流"创建科学研究专项课题(HSRP-DFCTCM-2023-2-21) （HSRP-DFCTCM-2023-2-21）
河南省中医药科学研究专项课题(2022JDZX102) Scientific Research Project of the Traditional Chinese Medicine(TCM)"Double First-Class"Establishment of Henan Province(HSRP-DFCTCM-2023-2-21) （2022JDZX102）
TCM Scientific Research Project of Henan Province(2022JDZX102) （2022JDZX102）
