针灸推拿医学（英文版）2025，Vol.23Issue(6)：538-545,8.DOI:10.1007/s11726-025-1534-9
捏脊联合不换金正气散治疗小儿厌食症的临床观察
Clinical observation of spine-pinching manipulation combined with Bu Huan Jin Zheng Qi San in the treatment of pediatric anorexia
摘要
Abstract
Objective:To observe the clinical efficacy of spine-pinching manipulation combined with Bu Huan Jin Zheng Qi San in the treatment of pediatric anorexia and its effects on serum gastrointestinal hormones,appetite-regulating factors,immune indicators,and nutritional status. Methods:A prospective randomized controlled trial design was adopted.A total of 180 children with pediatric anorexia were enrolled and divided into an observation group and a control group by the simple random grouping method,with 90 cases in each group.The control group was treated with modified Bu Huan Jin Zheng Qi San;the observation group was treated with spine-pinching manipulation therapy in addition to the same drug treatment as the control group.After 4 weeks of treatment,the two groups were compared in terms of clinical efficacy,changes in traditional Chinese medicine(TCM)symptom scores,serum gastrointestinal hormones(motilin and gastrin)levels,and serum appetite-regulating factors(neuropeptide Y,orexin,and leptin)levels.The nutritional status(serum zinc,serum calcium,and hemoglobin)and immune indicators[immunoglobulin(Ig)A,IgM,and IgG]were observed. Results:After treatment,the total effective rate in the observation group was 92.1%,higher than 82.9%in the control group(P<0.05).After treatment,the TCM symptom scores and serum leptin levels in both groups decreased compared to those before treatment(P<0.05),and those in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of serum motilin,gastrin,neuropeptide Y,orexin,serum zinc,serum calcium,hemoglobin,IgA,IgM,and IgG in both groups increased compared to those before treatment,and those in the observation group were higher than those in the control group(P<0.05). Conclusion:Compared to Bu Huan Jin Zheng Qi San alone,spine-pinching manipulation combined with Bu Huan Jin Zheng Qi San in the treatment of pediatric anorexia has better clinical efficacy,with more significant effects on improving serum gastrointestinal hormones,appetite-regulating factors,nutritional status,and immune indicators.关键词
推拿/按摩/捏脊/厌食/胃肠激素/食欲调节/营养指标/免疫功能Key words
Tuina/Massage/Spine-pinching Manipulation/Anorexia/Gastrointestinal Hormones/Appetite Regulation/Nutrition Assessment/Immune Function分类
医药卫生引用本文复制引用
FENG Shuo,LI Hexian,WU Lingjun,CUI Decheng,KONG Xiehe..捏脊联合不换金正气散治疗小儿厌食症的临床观察[J].针灸推拿医学（英文版）,2025,23(6):538-545,8.基金项目
This study was supported by the Hospital-level Research Project of Shunyi Hospital,Beijing Traditional Chinese Medicine Hospital(北京中医医院顺义医院院级课题项目,No.SYYJLC-202002). （北京中医医院顺义医院院级课题项目,No.SYYJLC-202002）
