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Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress

Pakit Boonpala Anusak Kijtawornrat Sushawadee Tongta Nakkawee Saengklub Vudhiporn Limprasutr Sirinapa Srikam Wilawan Ji-au Yaowalak Panyasing Sarawut Kumphune

动物模型与实验医学（英文）2025，Vol.8Issue(11)：2069-2079,11.
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动物模型与实验医学（英文）2025，Vol.8Issue(11)：2069-2079,11.DOI:10.1002/ame2.70093

Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress

Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress

Pakit Boonpala 1Anusak Kijtawornrat 1Sushawadee Tongta 2Nakkawee Saengklub 3Vudhiporn Limprasutr 4Sirinapa Srikam 5Wilawan Ji-au 6Yaowalak Panyasing 7Sarawut Kumphune8

作者信息

  • 1. Department of Physiology,Faculty of Veterinary Science,Chulalongkorn University,Bangkok,Thailand||Chulalongkorn University Laboratory Animal Center(CULAC),Chulalongkorn University,Bangkok,Thailand
  • 2. Chulalongkorn University Laboratory Animal Center(CULAC),Chulalongkorn University,Bangkok,Thailand
  • 3. Department of Physiology,Faculty of Pharmacy,Mahidol University,Bangkok,Thailand
  • 4. Chulalongkorn University Laboratory Animal Center(CULAC),Chulalongkorn University,Bangkok,Thailand||Department of Pharmacology and Physiology,Faculty of Pharmaceutical Sciences,Chulalongkorn University,Bangkok,Thailand
  • 5. Department of Pathology,Faculty of Medicine,Chulalongkorn University,Bangkok,Thailand
  • 6. Department of Pathology,King Chulalongkorn Memorial Hospital,Bangkok,Thailand
  • 7. Department of Pathology,Faculty of Veterinary Science,Chulalongkorn University,Bangkok,Thailand
  • 8. Biomedical Engineering Institute(BMEI),Chiang Mai University,Chiang Mai,Thailand||Biomedical Engineering and Innovation Research Centre,Chiang Mai University,Chiang Mai,Thailand
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摘要

关键词

apoptosis/endoplasmic reticulum(ER)stress/fibrosis/mitral regurgitation/mitral regurgitation rat model/pimobendan

Key words

apoptosis/endoplasmic reticulum(ER)stress/fibrosis/mitral regurgitation/mitral regurgitation rat model/pimobendan

引用本文复制引用

Pakit Boonpala,Anusak Kijtawornrat,Sushawadee Tongta,Nakkawee Saengklub,Vudhiporn Limprasutr,Sirinapa Srikam,Wilawan Ji-au,Yaowalak Panyasing,Sarawut Kumphune..Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress[J].动物模型与实验医学（英文）,2025,8(11):2069-2079,11.

基金项目

The 100th Anniversary Chulalongkorn University Fund for Doctoral Scholarship （）

the National Budget to CULAC,Grant/Award Number:390252002 （）

the 90th Anniversary of Chulalongkorn University Fund,Grant/Award Number:GCUGR1125641042D （）

the Thailand Science Research and Innovation Fund at Chulalongkorn University,Grant/Award Number:HEAF673100100 （）

动物模型与实验医学（英文）

2096-5451

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