广西医科大学学报2025，Vol.42Issue(6)：901-908,8.DOI:10.16190/j.cnki.45-1211/r.2025.06.014
改良学龄前儿童版龋病风险评估工具与Cariostat对龋病风险的预测效果对比
Evaluating the performance of the modified caries-risk assessment tool for preschool children versus the Cariostat test in predicting caries risk
摘要
Abstract
Objective:To compare the performance of the modified caries-risk assessment tool for preschool chil-dren(PSC-MCAT)and the Cariostat caries activity test in predicting caries risk among young children in Xixiang-tang District,Nanning,Guangxi,and to verify the feasibility of PSC-MCAT in predicting caries risk in young children in Guangxi.Methods:A prospective cohort study enrolled 511 three-year-old children from kindergar-tens in Xixiangtang District,Guangxi.At baseline,their caries risk was assessed with both PSC-MCAT and Cari-ostat.Comprehensive oral examinations were performed every six months for 1.5 years to compare the effective-ness of the two methods in predicting incident caries.Results:No statistically significant difference was observed in the caries risk levels assessed by the two methods(P＞0.05),and their agreement was poor(P＜0.05).At the 1.5-year follow-up,statistically significant differences in the mean new caries count were found among all three risk levels of the PSC-MCAT(P＜0.05).For the Cariostat,significant differences were only observed between the low-risk and high-risk groups and between the moderate-risk and high-risk groups(P＜0.05);within each baseline caries-risk level,no statistically significant differences in 1.5-year caries incidence or increment were ob-served between the two CRA methods for low-and moderate-risk children(P＞0.05).In the high-risk group,sta-tistically significant differences were observed in both caries incidence and increment(P＜0.05).Generalized lin-ear model analysis revealed a positive association between the risk levels assessed by both tools and the incidence of new caries.In the low-and moderate-risk levels,PSC-MCAT did not differ significantly from Cariostat(P＞0.05).In the high-risk level,a statistically significant difference was observed between the PSC-MCAT and Cari-ostat(P＜0.05),and PSC-MCAT was associated with an increased risk of new caries development(P＜0.05).The area under the receiver operating characteristic(ROC)the curve(AUC)for the PSC-MCAT was 0.634(95%CI:0.593-0.675),with a sensitivity of 92.55%and a specificity of 32.62%.The Cariostat yielded an AUC of 0.664(95%CI:0.622-0.701),with a sensitivity of 24.45%,and a specificity of 94.76%.Conclusion:The PSC-MCAT demonstrates considerable potential for caries risk assessment and prediction of new caries development,showing particular advantage in the initial screening of high-risk individuals.关键词
龋病/学龄前儿童/风险评估/预测效果/微生物标志方法Key words
caries/preschool children/risk assessment/prediction performance/microbial marker method分类
医药卫生引用本文复制引用
刘芳宏,王芳,蒋依玲,陈少勇,覃煜,黄子昱,刘思佳,邱荣敏..改良学龄前儿童版龋病风险评估工具与Cariostat对龋病风险的预测效果对比[J].广西医科大学学报,2025,42(6):901-908,8.基金项目
国家自然科学基金项目(No.82560199) （No.82560199）
广西壮族自治区科技厅重点研发计划项目(No.桂科AB22035015) （No.桂科AB22035015）
2024年广西医疗卫生适宜技术开发与推广应用项目(No.S2024121) （No.S2024121）
2023年国家级大学生创新创业训练计划项目(No.202310598053) （No.202310598053）
2024年广西壮族自治区大学生创新创业训练计划项目(No.S202410598220X) （No.S202410598220X）
