中北大学学报(自然科学版)2025,Vol.46Issue(6):734-741,8.DOI:10.62756/jnuc.issn.1673-3193.2025.02.0004
大鼠前进动作激活方法改进及速度调节实验研究
Research on the Improvement of Activation Methods and Speed Regulation of Forward Movement in Rats
罗祥宇 1张乐 1崔浩然 1何剑1
作者信息
- 1. 中北大学 电子测试技术重点实验室,山西 太原 030051||中北大学 铁电物理微纳器件与系统山西省重点实验室,山西 太原 030051
- 折叠
摘要
Abstract
To address the challenges of prolonged reward training and uncontrollable speed in activating forward movement during rat locomotion regulation,an optimized forward motion activation method of rats based on the traditional method and a speed-controllable regulation approach were proposed.The medial forebrain bundle(MFB)stimulation strategies were improved by investigating the regulatory mechanism of MFB electrical stimulation on rat forward locomotion.At the same time,speed-controllable modulation was achieved through adjustments in stimulation amplitude and frequency.It is found that the forward movement can be successfully activated without reward training using the optimized MFB electrical stimulation strategy,achieving a successful rate of movement execution exceeding 95%and the fastest controllable speed of 24.52 m/min.Compared with existing studies,this approach reduced the modeling time of speed-controllable rats markedly and realized precise regulation of rat forward movement utilizing lower stimulation parameters.关键词
大鼠运动调控/电刺激/内侧前脑束/前进动作/速度调节Key words
rat locomotion regulation/electrical stimulation/medial forebrain bundle/forward move-ment/speed regulation分类
信息技术与安全科学引用本文复制引用
罗祥宇,张乐,崔浩然,何剑..大鼠前进动作激活方法改进及速度调节实验研究[J].中北大学学报(自然科学版),2025,46(6):734-741,8.