湖南中医药大学学报2025，Vol.45Issue(12)：2335-2339,5.DOI:10.3969/j.issn.1674-070X.2025.12.012
电热针对气血两虚型癌因性疲乏患者中医证候及血清学指标的影响
Effects of electrothermal acupuncture on Chinese medicine pattern and serological indicators in patients with cancer-related fatigue of dual deficiency of qi and blood pattern
摘要
Abstract
Objective To investigate the effects of electrothermal acupuncture at Guanyuan(CV4),Shuidao(ST28),and Tituo(Ex-CA9)points on Chinese medicine pattern and serological indicators in patients with cancer-related fatigue(CRF)of dual deficiency of qi and blood pattern.Methods Sixty-six hospitalized patients undergoing chemotherapy were randomly divided into control group(n=33)and electrothermal acupuncture group(n=33).The control group received conventional symptomatic treatment(including analgesic and antiemetic medications),while the electrothermal acupuncture group received conventional treatment plus electrothermal acupuncture at Guanyuan(CV4),bilateral Shuidao(ST28),and bilateral Tituo(Ex-CA9)points,once daily for seven consecutive days.Chinese medicine pattern scores,clinical efficacy was evaluated,and serum levels of C-reactive protein(CRP),thyroid-stimulating hormone(TSH),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),and interferon-γ(IFN-γ)were measured in both groups before and after treatment;safety evaluation was performed throughout the trial.Results After treatment,the Chinese medicine pattern scores in the electrothermal acupuncture group were significantly lower than those before treatment(P<0.01)and also lower than those in the control group(P<0.01).The total effective rate in the electrothermal acupuncture group was 75.8%,which was significantly higher than the 42.4%in the control group(P<0.05).In the control group,IL-6 levels increased compared to those before treatment(P<0.05).In the electrothermal acupuncture group,IFN-γ levels decreased compared to those before treatment(P<0.05)and were lower than those in the control group(P<0.05).No statistically significant differences were observed in CRP,TSH,and TNF-α levels(P>0.05).No acupuncture-related adverse reactions occurred in either group during the trial.Conclusion Electrothermal acupuncture at Guanyuan(CV4),Shuidao(ST28),and Tituo(Ex-CA9)points can effectively alleviate fatigue and related patterns in patients with CRF of dual deficiency of qi and blood pattern.The mechanism of action may be associated with the modulation of IL-6 and IFN-γ levels.关键词
电热针/癌因性疲乏/气血两虚证/白细胞介素-6/干扰素-γKey words
electrothermal acupuncture/cancer-related fatigue/dual deficiency of qi and blood pattern/interleukin-6/interferon-γ分类
医药卫生引用本文复制引用
刘雅华,侯宇佳,杨传琦,芦殿荣,夏玉清..电热针对气血两虚型癌因性疲乏患者中医证候及血清学指标的影响[J].湖南中医药大学学报,2025,45(12):2335-2339,5.基金项目
北京中医药薪火传承"3+3"工程建设项目夏玉清名老中医传承工作室(京中医科字[2021]73号) （京中医科字[2021]73号）
中国中医科学院望京医院院级课题(WJYY-XZKT-2023-20). （WJYY-XZKT-2023-20）
